DRSC/TRiP Functional Genomics Resources

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Protein Alignment slp2 and Foxc2

DIOPT Version :9

Sequence 1:NP_476834.1 Gene:slp2 / 33608 FlyBaseID:FBgn0004567 Length:451 Species:Drosophila melanogaster
Sequence 2:NP_038547.2 Gene:Foxc2 / 14234 MGIID:1347481 Length:494 Species:Mus musculus


Alignment Length:367 Identity:115/367 - (31%)
Similarity:144/367 - (39%) Gaps:125/367 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   180 KPPYSYNALIMMAIRQSSEKRLTLNGIYEYIMTNHPYYRDNKQGWQNSIRHNLSLNKCFVKVPRH 244
            ||||||.|||.|||:.:.||::||||||::||...|:||:||||||||||||||||:|||||||.
Mouse    71 KPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRD 135

  Fly   245 YDDPGKGNYWMLDPSAEDVFIGGSTGKLRRR---------------------TTA---------- 278
            ...||||:||.|||.:.::|..||..:.|||                     |||          
Mouse   136 DKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVPKDKEERAHLKEPPSTTAKGAPTGTPVA 200

  Fly   279 ---ASRSRLAAFKRSLIGPMFPGLAAY----PQFGQFLTYPPTAPSLLASMYQRYNPFAPKGGPG 336
               ....:....|.....|..|.:...    |: |.....|.:|.|            .|.|.|.
Mouse   201 DGPKEAEKKVVVKSEAASPALPVITKVETLSPE-GALQASPRSASS------------TPAGSPD 252

  Fly   337 ------HPGLPPGLPGL---------PGPPGPQGPPGPP------PP---PFVAPPTSSELYQRL 377
                  |...|.||||.         ..|||....|...      ||   |:.|.|.::      
Mouse   253 GSLPEHHAAAPNGLPGFSVETIMTLRTSPPGGDLSPAAARAGLVVPPLALPYAAAPPAA------ 311

  Fly   378 QYQQLLHQHAAAAALAAHQRQL-SVAAASAASQP-----PPT----------------------- 413
             |.|...|...||..|.:|..: :::..:.|.:|     ||.                       
Mouse   312 -YTQPCAQGLEAAGSAGYQCSMRAMSLYTGAERPAHVCVPPALDEALSDHPSGPGSPLGALNLAA 375

  Fly   414 ----------HHHPHLAVGQAPLSPGGDSPGPSPQPLHKPVT 445
                      |||.|    ...|.|....|.|.|.|..:|.|
Mouse   376 GQEGALGASGHHHQH----HGHLHPQAPPPAPQPPPAPQPAT 413

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
slp2NP_476834.1 Forkhead 180..265 CDD:306709 57/84 (68%)
Foxc2NP_038547.2 FH 71..159 CDD:214627 58/87 (67%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 166..213 4/46 (9%)
EBP50_C 167..>257 CDD:286142 14/102 (14%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 233..267 10/46 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 381..422 12/37 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
54.820

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