DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slp2 and foxk2

DIOPT Version :9

Sequence 1:	NP_476834.1	Gene:	slp2 / 33608	FlyBaseID:	FBgn0004567	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_001135634.1	Gene:	foxk2 / 100216193	XenbaseID:	XB-GENE-483520	Length:	645	Species:	Xenopus tropicalis

Alignment Length:	405	Identity:	107/405 - (26%)
Similarity:	163/405 - (40%)	Gaps:	86/405 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 PESDLDVTSMSPAP-----VANPNESDPDEVDE------EFVEEDIECDGETTDGDAENKSNDGK 170
            |::...:.|..|:|     .||...|.|.....      ..:..|:..:...::.|.:....|
Frog   150 PDNMAHLISPLPSPTGTISAANSCPSSPRGAGSSGFKLGRVIPPDLIAEAAQSENDKDASGGD-- 212

  Fly   171 PVKDKKGNEKPPYSYNALIMMAIRQSSEKRLTLNGIYEYIMTNHPYYRDNKQGWQNSIRHNLSLN 235
               ..|.:.||||||..||:.||..:.:|:|||||||.:|..|:||||...:|||||||||||||
Frog   213 ---SPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLN 274

  Fly   236 KCFVKVPRHYDDPGKGNYWMLDPSAEDVFIGGSTGKLRRRTTAASRSRLAAFKRSLIGPMFPGLA 300
            :.|:||||..::||||::|.:||::|...:..:..|.|.|.....|:.|        ||:....|
Frog   275 RYFIKVPRSQEEPGKGSFWRIDPASESKLVEQAFRKRRPRGVPCFRTPL--------GPLSSRSA 331

  Fly   301 -AYPQFGQFLTYPPTAPSLLASMYQRYNPFAPKGGPGHPGLPPGLPGLPGPPGPQGPPGPP---- 360
             |.|.....|:...:......|:.:..:|...:..|.  .:.|.|..:......|..||.|
Frog   332 PASPNHAGVLSAHSSGLQTPESLSREGSPIPMEPEPS--AIQPKLAVIQEARFAQSAPGSPLSSQ 394

  Fly   361 ---------------PPPF-VAPPTSSELYQR--LQYQQLLHQHAAAAALAAH----------QR 397
                           |..: ||.|.::...|:  :|...::||..|.:.....          ..
Frog   395 QVLIAVQRQLPQTIKPVTYTVATPVTTATSQQALMQTVHVVHQIPAVSVTNVTGLTPINTYTVGG 459

  Fly   398 QLSVAAASAASQPP-------------------PTHHHPHLAVGQAPLSPGGDSP-------GPS 436
            |..||.|:..:||.                   |...||.|......:.....:|       ..:
Frog   460 QAMVAQAAVMAQPKLEPQENGDHKEVKVKVEAIPAIGHPALTTASRIIQTSSSAPLQTVTIVQQT 524

  Fly   437 PQPLHK-PVTVVSRN 450
            |...|: |:..|::|
Frog   525 PLGQHQLPIKAVTQN 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slp2	NP_476834.1	Forkhead	180..265	CDD:306709	50/84 (60%)
foxk2	NP_001135634.1	FHA	10..117	CDD:238017
foxk2	NP_001135634.1	Forkhead	218..304	CDD:365978	50/85 (59%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.040