DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slp1 and foxk2b

DIOPT Version :9

Sequence 1:	NP_476730.1	Gene:	slp1 / 33607	FlyBaseID:	FBgn0003430	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	XP_001922856.1	Gene:	foxk2b / 798356	ZFINID:	ZDB-GENE-030131-5310	Length:	597	Species:	Danio rerio

Alignment Length:	288	Identity:	87/288 - (30%)
Similarity:	137/288 - (47%)	Gaps:	47/288 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 KKPINTATQPIKTEPVHHHHQYVH---PYSNSDGELSASEDFDSPSRTSTPMSSAAESLSSQNND 81
            :.|:......|....::......|   |..:..|.:||:        .|.|.|......|.....
Zfish   123 ESPVKAVQPQISPLTINIPDNIAHLMSPLPSPTGTISAA--------NSCPSSPRGAGSSGYRLG 179

  Fly    82 KL--DVEFDDELEDQLDEDQESEDGNPSKKQKMTAGSDTKKPPYSYNALIMMAIQDSPEQRLTLN 144
            ::  |::..:: ..|.:.|:|:.:|:..|        |..||||||..||:.||..:|:::||||
Zfish   180 RIVPDLQLMND-NSQSENDKETSEGDSPK--------DDSKPPYSYAQLIVQAITMAPDKQLTLN 235

  Fly   145 GIYQYLINRFPYFKANKRGWQNSIRHNLSLNKCFTKIPRSYDDPGKGNYWILDPSAEEVFIGETT 209
            |||.::...:||::...:|||||||||||||:.|.|:|||.::||||::|.:|||:|...:.:..
Zfish   236 GIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPSSEGKLVEQAF 300

  Fly   210 GKLRRKNPGASRTRLA--AYRQAIFSP----MMAASPYG-------------APASSYGYPAVPF 255
            .|.|.:.....||.|.  :.|.|..||    :::|...|             .|..|......|.
Zfish   301 RKRRPRGVPCFRTPLGPLSSRSAPASPNHSGVLSAHSSGVQTPDSLSREGSPVPMESEPVSVPPP 365

  Fly   256 AAAAAAALYQRMNPAAYQAAYQQMQYQQ 283
            ||.|.||:..::      |..|:.::.|
Zfish   366 AAVAVAAVQPKL------AVIQETRFTQ 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slp1	NP_476730.1	FH	120..205	CDD:214627	47/84 (56%)
foxk2b	XP_001922856.1	FHA	17..109	CDD:238017
foxk2b	XP_001922856.1	Forkhead	211..297	CDD:278670	47/85 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850