DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slp1 and Foxj2

DIOPT Version :9

Sequence 1:	NP_476730.1	Gene:	slp1 / 33607	FlyBaseID:	FBgn0003430	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_068699.1	Gene:	Foxj2 / 60611	MGIID:	1926805	Length:	565	Species:	Mus musculus

Alignment Length:	297	Identity:	87/297 - (29%)
Similarity:	113/297 - (38%)	Gaps:	102/297 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 SEDGNPSKKQKMTAGSDTK----------------KPPYSYNALIMMAIQDSPEQRLTLNGIYQY 149
            |:.|.|...:|.:.||.|.                ||.|||..||..||..||.:::||:.||::
Mouse    31 SQAGPPGGARKCSPGSPTDPNATLSKDEAAVHQDGKPRYSYATLITYAINSSPAKKMTLSEIYRW 95

  Fly   150 LINRFPYFKANKRGWQNSIRHNLSLNKCFTKIPRSYDDPGKGNYWILDPSAEEVFIGETTGKLRR 214
            :.:.|||:|....||:|||||||||||||.|:||..||||||:||.:|...:       ..:.||
Mouse    96 ICDNFPYYKNAGIGWKNSIRHNLSLNKCFRKVPRPRDDPGKGSYWTIDTCPD-------ISRKRR 153

  Fly   215 KNPGASRTRLAAYRQAIFSP-------------------MMAASPYGAPASSYGYPAVPFAAAAA 260
            ..|....::.:..::|..||                   |...||......|.|..:|...|.||
Mouse   154 HPPDDDLSQDSPEQEASKSPRGGVPGSGEASLSHEGTPQMSLQSPSSVANYSQGPGSVDGGAVAA 218

  Fly   261 AA-------------------------------------LYQR------------------MNPA 270
            .|                                     ||:.                  |.|:
Mouse   219 GAPGQESTEGAPPLYNTNHDFKFSYSEINFQDLSWSFRNLYKSMLERSSSSQHGFSSLLGDMPPS 283

  Fly   271 AYQAAYQQMQYQQAPQAHHHQAPHPAQMQGYPQQLNA 307
            .....|||.|.||.|     ..|.|...|..|||..|
Mouse   284 NNYYVYQQQQQQQPP-----PQPQPPPQQPQPQQQQA 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slp1	NP_476730.1	FH	120..205	CDD:214627	46/84 (55%)
Foxj2	NP_068699.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	29..61		7/29 (24%)
		Forkhead	66..143	CDD:278670	45/76 (59%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	125..233		28/114 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	290..399		13/31 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	543..565
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820