DRSC/TRiP Functional Genomics Resources

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Protein Alignment slp1 and foxh1

DIOPT Version :9

Sequence 1:NP_476730.1 Gene:slp1 / 33607 FlyBaseID:FBgn0003430 Length:322 Species:Drosophila melanogaster
Sequence 2:NP_571577.1 Gene:foxh1 / 57930 ZFINID:ZDB-GENE-000616-15 Length:472 Species:Danio rerio


Alignment Length:235 Identity:74/235 - (31%)
Similarity:107/235 - (45%) Gaps:52/235 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    69 SSAAESLSSQNNDKLDVEFDDELEDQLDEDQ------------------ESEDGNPSKKQKMTAG 115
            ||:..|....:|..|      ||..:||:..                  |.:|||.|..:|... 
Zfish    35 SSSKRSCHRSSNPLL------ELGGRLDKSTGMAQDSCYRAKATNQGPWELQDGNSSGGKKKNY- 92

  Fly   116 SDTKKPPYSYNALIMMAIQDSPEQRLTLNGIYQYLINRFPYFKANKRGWQNSIRHNLSLNKCFTK 180
            ....||||||.|:|.|.||:|||::|||:.|.:.:...||:||.|.:||::|:|||||...||.|
Zfish    93 QRYPKPPYSYLAMIAMVIQNSPEKKLTLSEILKEISTLFPFFKGNYKGWRDSVRHNLSSYDCFVK 157

  Fly   181 IPRSYDDP-GKGNYWILDPSAEEVFIGETTGKLRRKNPGASR-------TRLAAYRQAIFSPMMA 237
            :.:....| ||||:|.::.:...:.:      |:|:|...||       ..||.|....:|....
Zfish   158 VLKDPGKPQGKGNFWTVEVNRIPLEL------LKRQNTAVSRQDETIFAQDLAPYIFQGYSQPNK 216

  Fly   238 ASPYGAPASSYGYPAVPFAAAAAAALYQRMNPAAYQAAYQ 277
            :.|. .|.||  .|.||          .|.:|...:..|:
Zfish   217 SKPL-PPESS--LPPVP----------TRQSPPPSEDPYR 243

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
slp1NP_476730.1 FH 120..205 CDD:214627 40/85 (47%)
foxh1NP_571577.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 36..56 6/25 (24%)
FH 97..174 CDD:238016 40/76 (53%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 211..246 11/46 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 261..360
SMAD-interaction domain (SID) 339..465
Fast/FoxH1 motif 1 (FM1) 357..361
Fast/FoxH1 motif 2 (FM2) 367..373
SMAD interaction motif (SIM) 428..448
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11829
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
43.920

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