DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slp1 and foxa4

DIOPT Version :9

Sequence 1:	NP_476730.1	Gene:	slp1 / 33607	FlyBaseID:	FBgn0003430	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_988938.1	Gene:	foxa4 / 394535	XenbaseID:	XB-GENE-486455	Length:	399	Species:	Xenopus tropicalis

Alignment Length:	230	Identity:	77/230 - (33%)
Similarity:	110/230 - (47%)	Gaps:	46/230 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 KPPYSYNALIMMAIQDSPEQRLTLNGIYQYLINRFPYFKANKRGWQNSIRHNLSLNKCFTKIPRS 184
            ||||||.:||.||||.:|.:.:|||.|||::|:.|||::.|::.|||||||:||.|.||.|:|||
Frog   119 KPPYSYISLITMAIQQAPNKMMTLNEIYQWIIDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVPRS 183

  Fly   185 YDDPGKGNYWILDPSAEEVFIGETTGKLRR-KNPGASRTRLAAYRQAIFSP------MMAASPYG 242
            .:.||||:||.|.|.:..:|  |....||| |.....|::.....:.:..|      .:..:|.|
Frog   184 PEKPGKGSYWTLHPESGNMF--ENGCYLRRQKRFKCERSKSGEREKKVNKPGDENGGSLKETPVG 246

  Fly   243 -APASSYGYPAVPF----AAAAAAALYQR-------MNPAAYQA-AYQQMQYQ-----------Q 283
             ...||...|..|.    ..:..::::|.       ::|.:.|| ...|:.|.           .
Frog   247 YDDCSSSRSPQAPVNDGGRDSTGSSIHQASGGSPVGLSPTSEQAGTASQLMYPLGLSNDGYLGLV 311

  Fly   284 APQAHHHQAP----HP---------AQMQGYPQQL 305
            ....|....|    ||         .|.|.||.:|
Frog   312 GEDVHLKHDPFSGRHPFSITQLMSSEQDQTYPSKL 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slp1	NP_476730.1	FH	120..205	CDD:214627	48/84 (57%)
foxa4	NP_988938.1	Forkhead_N	<25..118	CDD:369872
		COG5025	<118..303	CDD:227358	68/185 (37%)
		FH	119..207	CDD:214627	50/89 (56%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	219..290		10/70 (14%)
		HNF_C	326..387	CDD:370449	7/21 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910