DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slp1 and foxa3

DIOPT Version :9

Sequence 1:	NP_476730.1	Gene:	slp1 / 33607	FlyBaseID:	FBgn0003430	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_571374.1	Gene:	foxa3 / 30559	ZFINID:	ZDB-GENE-980526-423	Length:	441	Species:	Danio rerio

Alignment Length:	202	Identity:	72/202 - (35%)
Similarity:	101/202 - (50%)	Gaps:	31/202 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 VHPYSNSDGELSASE---DFDSPSRTSTPMSSAAESLSSQNNDKLDVEFDDELEDQLDEDQESED 103
            ::.|.|.:...|.|.   .:.|....|:|:||.....:..:...:....:.....||. ...|..
Zfish    38 LNSYINLNSACSTSSMNMGYPSAGLNSSPLSSMGGGPNHMSLSPVGSSLNPSSLTQLG-SSASTL 101

  Fly   104 GNPSKKQKM------------TAGSDTK-------------KPPYSYNALIMMAIQDSPEQRLTL 143
            |..|..|.|            |:.:.||             ||||||.:||.||||.|..:.|||
Zfish   102 GPLSHYQSMGQPMSQISYPSPTSLNRTKEMPKPYRRSLTHAKPPYSYISLITMAIQQSQSKMLTL 166

  Fly   144 NGIYQYLINRFPYFKANKRGWQNSIRHNLSLNKCFTKIPRSYDDPGKGNYWILDPSAEEVFIGET 208
            |.|||::::.|||::.|::.|||||||:||.|.||.|:.||.|.||||:||.|.|::..:|  |.
Zfish   167 NEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPNSGNMF--EN 229

  Fly   209 TGKLRRK 215
            ...|||:
Zfish   230 GCYLRRQ 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slp1	NP_476730.1	FH	120..205	CDD:214627	48/84 (57%)
foxa3	NP_571374.1	Forkhead_N	17..142	CDD:254796	19/104 (18%)
		FH	143..231	CDD:214627	50/89 (56%)
		HNF_C	374..>408	CDD:286443
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910