DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment slp1 and Foxk1

DIOPT Version :9

Sequence 1:	NP_476730.1	Gene:	slp1 / 33607	FlyBaseID:	FBgn0003430	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001032296.2	Gene:	Foxk1 / 304298	RGDID:	1309643	Length:	719	Species:	Rattus norvegicus

Alignment Length:	236	Identity:	75/236 - (31%)
Similarity:	117/236 - (49%)	Gaps:	32/236 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 KPINTATQPIKTE-PVHHHHQYVHPYSNSDGELSASEDFDSPSRTSTPMSSAAESLSSQNNDKLD 84
            :|:.....|:|.. |.......|.|..:..|.:|...     |..::|..:.:.|.....|...|
  Rat   202 RPLYPQISPLKIHIPEPDLRSLVSPIPSPTGTISVPN-----SCPASPRGAGSSSYRFVQNVTSD 261

  Fly    85 VEFDDELEDQLDEDQESE-DGNPSKKQKMTAGSDTKKPPYSYNALIMMAIQDSPEQRLTLNGIYQ 148
            ::...|...:...:|::: .|..|.|       |..||||||..||:.||..:.:::|||:|||.
  Rat   262 LQLAAEFAAKAASEQQADTSGGDSPK-------DESKPPYSYAQLIVQAISSAQDRQLTLSGIYA 319

  Fly   149 YLINRFPYFKANKRGWQNSIRHNLSLNKCFTKIPRSYDDPGKGNYWILDPSAEEVFIGETTGKLR 213
            ::...:||::...:|||||||||||||:.|.|:|||.::||||::|.:||::|...:.:...|.|
  Rat   320 HITKHYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASEAKLVEQAFRKRR 384

  Fly   214 RKNPGASRTRLAAYRQAIFSPMMAASPYGAPASSYGYPAVP 254
            ::.....||                 |:| |.||...||.|
  Rat   385 QRGVSCFRT-----------------PFG-PLSSRSAPASP 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slp1	NP_476730.1	FH	120..205	CDD:214627	44/84 (52%)
Foxk1	NP_001032296.2	FHA	<88..190	CDD:224630
		FHA	96..189	CDD:238017
		Forkhead	291..377	CDD:278670	44/85 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820