DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slp1 and Foxk2

DIOPT Version :9

Sequence 1:	NP_476730.1	Gene:	slp1 / 33607	FlyBaseID:	FBgn0003430	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	XP_006247952.1	Gene:	Foxk2 / 303753	RGDID:	1305408	Length:	650	Species:	Rattus norvegicus

Alignment Length:	329	Identity:	90/329 - (27%)
Similarity:	136/329 - (41%)	Gaps:	79/329 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 KPINTATQPIKTEPVHHHHQYVHPYSNSDGELSASEDFDSPSRTSTPMSSAAESLSSQNNDKLDV 85
            ||:.....|:...........:.|..:..|.:||:....|..|.:   .|:...:.......|::
  Rat   164 KPVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGA---GSSGYKMGRVIPSDLNL 225

  Fly    86 EFDDELEDQLDEDQESEDGNPSKKQKMTAGSDTKKPPYSYNALIMMAIQDSPEQRLTLNGIYQYL 150
            ..|:   .|.:.::|:..|:..|        |..||||||..||:.||..:|:::|||||||.::
  Rat   226 MADN---SQPENEKEASGGDSPK--------DDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHI 279

  Fly   151 INRFPYFKANKRGWQNSIRHNLSLNKCFTKIPRSYDDPGKGNYWILDPSAEEVFIGETTGKLRRK 215
            ...:||::...:|||||||||||||:.|.|:|||.::||||::|.:||::|...:.:...|.|.:
  Rat   280 TKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLVEQAFRKRRPR 344

  Fly   216 ---------------------------------------------------NPGASRTRLAAYRQ 229
                                                               .||||:.:||..::
  Rat   345 GVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGASQPKLAVIQE 409

  Fly   230 AIFSPMMAASPYGAPASSYGYPAVPFAAAAAAALYQRMNPAAYQAAYQQMQYQQAP---QAHH-- 289
            |.|    |.|..|:|.||.     |........|...:.|..|..|.........|   |..|
  Rat   410 ARF----AQSAPGSPLSSQ-----PVLITVQRQLPPAIKPVTYTVATPVTTPTSQPPVVQTVHVV 465

  Fly   290 HQAP 293
            ||.|
  Rat   466 HQIP 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slp1	NP_476730.1	FH	120..205	CDD:214627	46/84 (55%)
Foxk2	XP_006247952.1	FHA	41..145	CDD:238017
Foxk2	XP_006247952.1	Forkhead	249..335	CDD:278670	46/85 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820