DRSC/TRiP Functional Genomics Resources

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Protein Alignment slp1 and foxa2

DIOPT Version :9

Sequence 1:NP_476730.1 Gene:slp1 / 33607 FlyBaseID:FBgn0003430 Length:322 Species:Drosophila melanogaster
Sequence 2:NP_571024.1 Gene:foxa2 / 30126 ZFINID:ZDB-GENE-980526-404 Length:409 Species:Danio rerio


Alignment Length:355 Identity:97/355 - (27%)
Similarity:159/355 - (44%) Gaps:68/355 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MVKSEMEFKSNFSIDAILAKKPINTATQPIKTEPVHHHHQYVHPYSNSDGELSASEDFDSP--SR 63
            |..|.|...:|.:....:....:||...|..|.        :.|.:.:...:.|.....|.  |.
Zfish    45 MTMSGMSSTANMTAANTMNMSYVNTGMSPSMTG--------MSPGTGAMAGMGAGMTGMSAALSP 101

  Fly    64 TSTPMSSAAES---LSSQNNDKLDVEFDDELEDQLDEDQESEDGNPSKKQKMTAGSDT-KKPPYS 124
            |.:||::.|.|   |:|.:|           .:.:.......:.|.|:..|....|.| .|||||
Zfish   102 TMSPMAAQAPSMNALTSYSN-----------MNAMSPMYGQSNINRSRDPKTYRRSYTHAKPPYS 155

  Fly   125 YNALIMMAIQDSPEQRLTLNGIYQYLINRFPYFKANKRGWQNSIRHNLSLNKCFTKIPRSYDDPG 189
            |.:||.||||.||.:.|||:.|||::::.||:::.|::.|||||||:||.|.||.|:|||.|.||
Zfish   156 YISLITMAIQQSPSKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPG 220

  Fly   190 KGNYWILDPSAEEVFIGETTGKLRRKNPGASRTRLAAYRQAIFSPMMAASPYGAPASSYGYPA-- 252
            ||::|.|.|.:..:|  |....|||:.      |....::....|....|..|:.:||.....  
Zfish   221 KGSFWTLHPDSGNMF--ENGCYLRRQK------RFKCDKKLSKDPSRKTSEGGSNSSSESCNGNE 277

  Fly   253 VPFAAAAAAALY---------QRMNPAAYQAAYQQMQYQQA-------------PQAHHHQAPHP 295
            .|.:.:::..|.         |.::|....:...|.|:..|             |: ||:...||
Zfish   278 SPHSNSSSNELKRSLSDMKSGQGLSPDHAASPTSQAQHLLAQHHSVLAHEGHLKPE-HHYSFNHP 341

  Fly   296 --------AQMQGYPQQLNAELFQRMQFFG 317
                    ::.|.:  :::.:.::::..:|
Zfish   342 FSINNLMSSEQQHH--KMDLKTYEQVMHYG 369

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
slp1NP_476730.1 FH 120..205 CDD:214627 47/84 (56%)
foxa2NP_571024.1 Forkhead_N 18..150 CDD:254796 25/123 (20%)
FH 151..239 CDD:214627 49/89 (55%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 250..315 10/64 (16%)
HNF_C 340..398 CDD:286443 4/32 (13%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

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