DRSC/TRiP Functional Genomics Resources

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Protein Alignment slp1 and FOXB1

DIOPT Version :9

Sequence 1:NP_476730.1 Gene:slp1 / 33607 FlyBaseID:FBgn0003430 Length:322 Species:Drosophila melanogaster
Sequence 2:NP_036314.2 Gene:FOXB1 / 27023 HGNCID:3799 Length:325 Species:Homo sapiens


Alignment Length:217 Identity:80/217 - (36%)
Similarity:108/217 - (49%) Gaps:45/217 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   119 KKPPYSYNALIMMAIQDSPEQRLTLNGIYQYLINRFPYFKANKRGWQNSIRHNLSLNKCFTKIPR 183
            :||||||.:|..||||.|||:.|.|:.||:::::||||::.|.:.||||:|||||.|.||.||||
Human    12 QKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPR 76

  Fly   184 SYDDPGKGNYWILDPSAEEVFIGETTGKLRRK--------------NPG--------ASRTRLAA 226
            ..|.||||::|.|.||..::|  |....|||:              .|.        .::.||:|
Human    77 RPDQPGKGSFWALHPSCGDMF--ENGSFLRRRKRFKVLKSDHLAPSKPADAAQYLQQQAKLRLSA 139

  Fly   227 Y-RQAIFSPMMAASPY--GAPASSYGYPAVPFAAAAAAALYQRMNPAAYQAAYQQMQYQQAPQAH 288
            . ......|.|.|:.|  |..|...|:.. |||.....|...:| |..  .|:..|  |..|.|:
Human   140 LAASGTHLPQMPAAAYNLGGVAQPSGFKH-PFAIENIIAREYKM-PGG--LAFSAM--QPVPAAY 198

  Fly   289 HHQAPHPAQM--------QGYP 302
                |.|.|:        .|:|
Human   199 ----PLPNQLTTMGSSLGTGWP 216

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
slp1NP_476730.1 FH 120..205 CDD:214627 48/84 (57%)
FOXB1NP_036314.2 FH_FOXB2 1..110 CDD:410817 53/99 (54%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 284..325
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2114
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.940

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