DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slp1 and Foxi3

DIOPT Version :9

Sequence 1:	NP_476730.1	Gene:	slp1 / 33607	FlyBaseID:	FBgn0003430	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001094934.1	Gene:	Foxi3 / 232077	MGIID:	3511278	Length:	399	Species:	Mus musculus

Alignment Length:	230	Identity:	82/230 - (35%)
Similarity:	112/230 - (48%)	Gaps:	59/230 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 ASEDFDSPSRT--STPMSSAAES----LSSQNNDKLDVEFDDELEDQLDEDQESEDGNPSKKQKM 112
            |...|..||.:  ::|..|||..    ||..:.:.|                          .||
Mouse    89 AQRGFAQPSASAPASPAGSAAPGELGWLSMASREDL--------------------------MKM 127

  Fly   113 TAGSDTKKPPYSYNALIMMAIQDSPEQRLTLNGIYQYLINRFPYFKANKRGWQNSIRHNLSLNKC 177
            .      :|||||:|||.||||.:||::|||:.|||::.:.||:::.:|.|||||||||||||.|
Mouse   128 V------RPPYSYSALIAMAIQSAPERKLTLSHIYQFVADNFPFYQRSKAGWQNSIRHNLSLNDC 186

  Fly   178 FTKIPRSYDDPGKGNYWILDPSAEEVFIGETTGKLRRKN-------------PGASRTRLAAYRQ 229
            |.|:||..|||||||||.|||:.|::|   ..|..|||.             .|.|::...:.|.
Mouse   187 FKKVPRDEDDPGKGNYWTLDPNCEKMF---DNGNFRRKRRRRAEASSNLTVPSGTSKSEGQSSRL 248

  Fly   230 AIFSPMMAASPYG--APASSYGYPAVPFAAAAAAA 262
            .:...:...||..  .|:.|   |..|....:.|:
Mouse   249 RVSGKLEGDSPSSILRPSQS---PEPPEGTKSTAS 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slp1	NP_476730.1	FH	120..205	CDD:214627	54/84 (64%)
Foxi3	NP_001094934.1	Forkhead	129..215	CDD:278670	55/88 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920