DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slp1 and Foxj3

DIOPT Version :9

Sequence 1:	NP_476730.1	Gene:	slp1 / 33607	FlyBaseID:	FBgn0003430	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001344106.1	Gene:	Foxj3 / 230700	MGIID:	2443432	Length:	623	Species:	Mus musculus

Alignment Length:	224	Identity:	78/224 - (34%)
Similarity:	108/224 - (48%)	Gaps:	58/224 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 PSRTSTPMSSAAE-SLSS-------------QNND-----------KLDVEFDDELEDQLDEDQE 100
            ||.||..|:|..| ||:|             |.:|           |.:...|.......:|.|:
Mouse     9 PSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKKNALLDPNTTLDQEEVQQ 73

  Fly   101 SEDGNPSKKQKMTAGSDTKKPPYSYNALIMMAIQDSPEQRLTLNGIYQYLINRFPYFKANKRGWQ 165
            .:||               ||||||.:||..||..||::::||:.|||::.:.|||::....||:
Mouse    74 HKDG---------------KPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWK 123

  Fly   166 NSIRHNLSLNKCFTKIPRSYDDPGKGNYWILDPSAEEVFIGETTGKLRRKNPGASRTRLAAYRQA 230
            |||||||||||||.|:|||.||||||:||.:|.:.:     |.|...|.|....|..|
Mouse   124 NSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPK-----EDTLPTRPKKRARSVER------- 176

  Fly   231 IFSPMMAASPYGAPASSYGYPAVPFAAAA 259
                  |::||...:.|.|...:...:|:
Mouse   177 ------ASTPYSIDSDSLGMECIISGSAS 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slp1	NP_476730.1	FH	120..205	CDD:214627	48/84 (57%)
Foxj3	NP_001344106.1	COG5025	<54..347	CDD:227358	66/179 (37%)
		Forkhead	78..155	CDD:365978	47/76 (62%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	143..178		15/52 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	248..275
		PAT1	<311..>434	CDD:370676
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	316..451
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820