DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slp1 and FOXS1

DIOPT Version :9

Sequence 1:	NP_476730.1	Gene:	slp1 / 33607	FlyBaseID:	FBgn0003430	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_004109.1	Gene:	FOXS1 / 2307	HGNCID:	3735	Length:	330	Species:	Homo sapiens

Alignment Length:	178	Identity:	74/178 - (41%)
Similarity:	94/178 - (52%)	Gaps:	41/178 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 SDTKKPPYSYNALIMMAIQDSPEQRLTLNGIYQYLINRFPYFKANKRGWQNSIRHNLSLNKCFTK 180
            ::..||||||.|||.||||.||.||.||:|||:|::.||.:::.|:.|||||||||||||:||.|
Human    14 TEPTKPPYSYIALIAMAIQSSPGQRATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVK 78

  Fly   181 IPRSYDDPGKGNYWILDPSAEEVFIGETTGKLRR-----KNPGASRTRLAAY------------- 227
            :||....||||:||.|||...::|  |....|||     :..||..||..|.
Human    79 VPRDDRKPGKGSYWTLDPDCHDMF--EHGSFLRRRRRFTRQTGAEGTRGPAKARRGPLRATSQDP 141

  Fly   228 --------RQAIFSP------------MMAASPYG-APASSYGYPAVP 254
                    ||..|.|            ::.|.|.. .||::.|.|..|
Human   142 GVPNATTGRQCSFPPELPDPKGLSFGGLVGAMPASMCPATTDGRPRPP 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slp1	NP_476730.1	FH	120..205	CDD:214627	53/84 (63%)
FOXS1	NP_004109.1	Forkhead	18..103	CDD:306709	54/86 (63%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	111..157		8/45 (18%)
		DNA_pol3_gamma3	<116..313	CDD:331207	16/74 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	179..200		5/11 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820