DRSC/TRiP Functional Genomics Resources

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Protein Alignment slp1 and FOXD2

DIOPT Version :9

Sequence 1:NP_476730.1 Gene:slp1 / 33607 FlyBaseID:FBgn0003430 Length:322 Species:Drosophila melanogaster
Sequence 2:NP_004465.3 Gene:FOXD2 / 2306 HGNCID:3803 Length:495 Species:Homo sapiens


Alignment Length:302 Identity:105/302 - (34%)
Similarity:130/302 - (43%) Gaps:83/302 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    89 DELEDQLDEDQES----EDGNP----SKKQKMTAGSD-----------------------TK--- 119
            :|.|..|.||:|.    .||.|    |:.....|||.                       |:   
Human    61 EEAEADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPGPGPPSGGAATRSPL 125

  Fly   120 -KPPYSYNALIMMAIQDSPEQRLTLNGIYQYLINRFPYFKANKRGWQNSIRHNLSLNKCFTKIPR 183
             ||||||.|||.|||..||::||||:.|.:::..||||::.....||||||||||||.||.||||
Human   126 VKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPR 190

  Fly   184 SYDDPGKGNYWILDPSAEEVFIGETTGKLRRK-------------------------------NP 217
            ...:|||||||.|||.:.::|  :....|||:                               :|
Human   191 EPGNPGKGNYWTLDPESADMF--DNGSFLRRRKRFKRQPLPPPHPHPHPHPELLLRGGAAAAGDP 253

  Fly   218 GASRTRLAAYRQAIFSPMMAASPYGAP---ASSYGYP---AVPFAAAAAAALYQRMNPAAYQAAY 276
            ||.....|||....:...:|...||||   .:.:.:|   |..||||||||..|...|....||.
Human   254 GAFLPGFAAYGAYGYGYGLALPAYGAPPPGPAPHPHPHPHAFAFAAAAAAAPCQLSVPPGRAAAP 318

  Fly   277 QQMQYQQAPQAHHHQAPHPAQMQ---------GYPQQLNAEL 309
            .......:..|....||.||...         |.|..|.|||
Human   319 PPGPPTASVFAGAGSAPAPAPASGSGPGPGPAGLPAFLGAEL 360

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
slp1NP_476730.1 FH 120..205 CDD:214627 51/84 (61%)
FOXD2NP_004465.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 14..122 13/60 (22%)
Forkhead 127..213 CDD:278670 52/87 (60%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 312..347 7/34 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 397..444
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11829
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
54.920

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