DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slp1 and FOXI1

DIOPT Version :9

Sequence 1:	NP_476730.1	Gene:	slp1 / 33607	FlyBaseID:	FBgn0003430	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_036320.2	Gene:	FOXI1 / 2299	HGNCID:	3815	Length:	378	Species:	Homo sapiens

Alignment Length:	167	Identity:	75/167 - (44%)
Similarity:	102/167 - (61%)	Gaps:	18/167 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 PSKKQKMTAGSDTKKPPYSYNALIMMAIQDSPEQRLTLNGIYQYLINRFPYFKANKRGWQNSIRH 170
            ||:::.|    ...:|||||:|||.|||..:|::||||:.||||:.:.||::..:|.||||||||
Human   113 PSQEELM----KLVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRH 173

  Fly   171 NLSLNKCFTKIPRSYDDPGKGNYWILDPSAEEVF-IGETTGKLRRKNPGASRTRLAAYRQA---- 230
            |||||.||.|:||..|||||||||.|||:.|::| .|....|.:||:..:|.|...|..:.
Human   174 NLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDVSSSTASLALEKTESSL 238

  Fly   231 -IFSP--------MMAASPYGAPASSYGYPAVPFAAA 258
             :.||        :..|||.|..:|....|:.|.:.|
Human   239 PVDSPKTTEPQDILDGASPGGTTSSPEKRPSPPPSGA 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slp1	NP_476730.1	FH	120..205	CDD:214627	55/85 (65%)
FOXI1	NP_036320.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		FH	123..211	CDD:214627	55/87 (63%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	208..278		17/68 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820