DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bowl and MSN2

DIOPT Version :9

Sequence 1:	NP_001245861.1	Gene:	bowl / 33602	FlyBaseID:	FBgn0004893	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_013751.1	Gene:	MSN2 / 855053	SGDID:	S000004640	Length:	704	Species:	Saccharomyces cerevisiae

Alignment Length:	127	Identity:	33/127 - (25%)
Similarity:	50/127 - (39%)	Gaps:	48/127 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 RRLLRAPGRASRPKKQFICKFCNRQFTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDH-R 285
            ||....|.|.|                   :::|......:|:|:.|.||.|:|:|.:||:.| |
Yeast   622 RRKSMTPSRRS-------------------SVVIESTKELEEKPFHCHICPKSFKRSEHLKRHVR 667

  Fly   286 YIHSKEKPFKCTECGKGFCQSRTLAVHKILHMEESPHKCPVCSRSFNQRSNLKTHLLTHTDH 347
            .:||.|:||.|                         |   :|.:.|::..||..|:.||..|
Yeast   668 SVHSNERPFAC-------------------------H---ICDKKFSRSDNLSQHIKTHKKH 701

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bowl	NP_001245861.1	COG5048	<232..372	CDD:227381	29/117 (25%)
		C2H2 Zn finger	240..260	CDD:275368	1/19 (5%)
		zf-H2C2_2	252..277	CDD:290200	8/24 (33%)
		C2H2 Zn finger	268..288	CDD:275368	10/20 (50%)
		zf-H2C2_2	280..303	CDD:290200	10/23 (43%)
		C2H2 Zn finger	296..316	CDD:275368	1/19 (5%)
		zf-C2H2	322..344	CDD:278523	6/21 (29%)
		C2H2 Zn finger	324..344	CDD:275368	5/19 (26%)
		zf-H2C2_2	336..361	CDD:290200	6/12 (50%)
		C2H2 Zn finger	352..372	CDD:275368
MSN2	NP_013751.1	COG5048	127..594	CDD:227381
		zf-C2H2_4	647..670	CDD:404733	10/22 (45%)
		C2H2 Zn finger	649..670	CDD:275368	10/20 (50%)
		zf-H2C2_2	661..687	CDD:404364	13/53 (25%)
		zf-C2H2	676..698	CDD:395048	8/49 (16%)
		C2H2 Zn finger	678..698	CDD:275368	7/47 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030