DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bowl and egr4

DIOPT Version :9

Sequence 1:	NP_001245861.1	Gene:	bowl / 33602	FlyBaseID:	FBgn0004893	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_001107925.1	Gene:	egr4 / 795099	ZFINID:	ZDB-GENE-080204-90	Length:	352	Species:	Danio rerio

Alignment Length:	188	Identity:	57/188 - (30%)
Similarity:	77/188 - (40%)	Gaps:	20/188 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   157 PGGPGGPGVPPPGVLYGPAGVPPPPYLTGPGPSPTGAGSFPFPPGAAAAALFPPGLGPGMHAGLD 221
            |.||....|....:...|.....|   ..|.||...:....||.....|......|....||  .
Zfish   175 PLGPETDSVLDTWIKQEPLDFQLP---VAPAPSHENSLYISFPNAFGLADALDSLLATNTHA--Q 234

  Fly   222 RRLLRAPGRASRPKKQFIC--KFCNRQFTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDH 284
            |...||...|:| :|.|.|  :.|.|:|::|..|..|.|.||..:|:.|.:|.:.|.|.|||..|
Zfish   235 RSKPRARKGAAR-EKPFSCPVESCERRFSRSDELNRHVRIHTGHKPFQCRVCLRCFSRSDHLTTH 298

  Fly   285 RYIHSKEKPFKCTECGKGFCQSRTLAVHKILHMEESPHKCPVCSRSFNQRSNLKTHLL 342
            ...|:.||||.|..|.:.|.:|.....|..:|:::            .:|...||.||
Zfish   299 MRTHTGEKPFSCDVCARRFARSDERKRHMRVHLKQ------------RERMQQKTELL 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bowl	NP_001245861.1	COG5048	<232..372	CDD:227381	38/113 (34%)
		C2H2 Zn finger	240..260	CDD:275368	8/21 (38%)
		zf-H2C2_2	252..277	CDD:290200	9/24 (38%)
		C2H2 Zn finger	268..288	CDD:275368	8/19 (42%)
		zf-H2C2_2	280..303	CDD:290200	10/22 (45%)
		C2H2 Zn finger	296..316	CDD:275368	5/19 (26%)
		zf-C2H2	322..344	CDD:278523	5/21 (24%)
		C2H2 Zn finger	324..344	CDD:275368	5/19 (26%)
		zf-H2C2_2	336..361	CDD:290200	4/7 (57%)
		C2H2 Zn finger	352..372	CDD:275368
egr4	NP_001107925.1	COG5048	229..>311	CDD:227381	33/84 (39%)
		C2H2 Zn finger	252..274	CDD:275368	8/21 (38%)
		zf-H2C2_2	266..291	CDD:290200	9/24 (38%)
		COG5048	278..>344	CDD:227381	23/77 (30%)
		C2H2 Zn finger	282..302	CDD:275368	8/19 (42%)
		zf-H2C2_2	294..319	CDD:290200	11/24 (46%)
		C2H2 Zn finger	310..330	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030