DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment bowl and Sp2

DIOPT Version :9

Sequence 1:NP_001245861.1 Gene:bowl / 33602 FlyBaseID:FBgn0004893 Length:744 Species:Drosophila melanogaster
Sequence 2:NP_084496.2 Gene:Sp2 / 78912 MGIID:1926162 Length:613 Species:Mus musculus


Alignment Length:314 Identity:63/314 - (20%)
Similarity:92/314 - (29%) Gaps:131/314 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 IPMLRPSRMDQFMNSMAAAAAA-------VGG---GGLPGAADRNGGSGGSDGGSQNGNGDSRNS 72
            :|.:.|:.....:|:...||||       :.|   .|:|......||.......:.:||    |.
Mouse   412 LPKIAPAGSIISLNAAQLAAAAQAMQTININGVQVQGVPVTITNTGGQQQLTVQNVSGN----NL 472

  Fly    73 SASRISAYETQLAYQQHLAGLHGPPPPPPPSHHREISAFVPVLPTGKVRPGSNSNYEIIAMMADK 137
            :.|.:|..:.||..:|.|||     ...|....|.::...|....|:.|.|...           
Mouse   473 TISGLSPTQIQLQMEQALAG-----EAQPGEKRRRMACTCPNCKDGEKRSGEQG----------- 521

  Fly   138 RKELALREAAAAAAMLGRGPGGPGGPGVPPPGVLYGPAGVPPPPYLTGPGPSPTGAGSFPFPPGA 202
                                                                             
Mouse   522 ----------------------------------------------------------------- 521

  Fly   203 AAAALFPPGLGPGMHAGLDRRLLRAPGRASRPKKQFICKF--CNRQFTKSYNLLIHERTHTDERP 265
                                            ||:.:|..  |.:.|.|:..|..|.|.||.|||
Mouse   522 --------------------------------KKKHVCHIPDCGKTFRKTSLLRAHVRLHTGERP 554

  Fly   266 YSCD--ICGKAFRRQDHLRDHRYIHSKEKPFKCTECGKGFCQSRTLAVHKILHM 317
            :.|:  .|||.|.|.|.|:.|...|:.:|.|:|.:|.|.|.:|..|..|...|:
Mouse   555 FVCNWFFCGKRFTRSDELQRHARTHTGDKRFECAQCQKRFMRSDHLTKHYKTHL 608

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
bowlNP_001245861.1 COG5048 <232..372 CDD:227381 34/90 (38%)
C2H2 Zn finger 240..260 CDD:275368 7/21 (33%)
zf-H2C2_2 252..277 CDD:290200 13/26 (50%)
C2H2 Zn finger 268..288 CDD:275368 9/21 (43%)
zf-H2C2_2 280..303 CDD:290200 8/22 (36%)
C2H2 Zn finger 296..316 CDD:275368 7/19 (37%)
zf-C2H2 322..344 CDD:278523
C2H2 Zn finger 324..344 CDD:275368
zf-H2C2_2 336..361 CDD:290200
C2H2 Zn finger 352..372 CDD:275368
Sp2NP_084496.2 zf-C2H2 525..549 CDD:278523 7/23 (30%)
C2H2 Zn finger 530..549 CDD:275368 6/18 (33%)
zf-H2C2_2 542..568 CDD:290200 13/25 (52%)
C2H2 Zn finger 557..579 CDD:275368 9/21 (43%)
zf-H2C2_2 571..594 CDD:290200 8/22 (36%)
zf-C2H2 585..607 CDD:278523 8/21 (38%)
C2H2 Zn finger 587..607 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2698
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.030

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