DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment bowl and osr2

DIOPT Version :9

Sequence 1:NP_001245861.1 Gene:bowl / 33602 FlyBaseID:FBgn0004893 Length:744 Species:Drosophila melanogaster
Sequence 2:XP_005173612.1 Gene:osr2 / 550389 ZFINID:ZDB-GENE-050417-183 Length:278 Species:Danio rerio


Alignment Length:221 Identity:139/221 - (62%)
Similarity:150/221 - (67%) Gaps:36/221 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   181 PYLTGPGPSPTGAGSFPFPPGAAAAALFP--------------------------PGLGPGMHAG 219
            |.|.|.. .|...|:.|||  ||||.|.|                          |.:.......
Zfish    55 PQLQGLA-DPRFPGALPFP--AAAAHLLPHKHPVHRKDRPRFDFANLAVAATQEDPPVTGQSRLS 116

  Fly   220 LDRRLLRAPGRASRP---KKQFICKFCNRQFTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHL 281
            .:||    |.|...|   ||:|||:||.|.||||||||||||||||||||:||||.|||||||||
Zfish   117 PERR----PARGRLPAKSKKEFICRFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHL 177

  Fly   282 RDHRYIHSKEKPFKCTECGKGFCQSRTLAVHKILHMEESPHKCPVCSRSFNQRSNLKTHLLTHTD 346
            |||||||||||||||.||||||||||||||||.||::|||||||.|.|:||||||||||||||||
Zfish   178 RDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHLQESPHKCPTCGRTFNQRSNLKTHLLTHTD 242

  Fly   347 HKPYECSSCGKVFRRNCDLRRHALTH 372
            .||:.|..||||||||||||||:|||
Zfish   243 LKPFCCGRCGKVFRRNCDLRRHSLTH 268

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
bowlNP_001245861.1 COG5048 <232..372 CDD:227381 118/142 (83%)
C2H2 Zn finger 240..260 CDD:275368 16/19 (84%)
zf-H2C2_2 252..277 CDD:290200 22/24 (92%)
C2H2 Zn finger 268..288 CDD:275368 18/19 (95%)
zf-H2C2_2 280..303 CDD:290200 21/22 (95%)
C2H2 Zn finger 296..316 CDD:275368 17/19 (89%)
zf-C2H2 322..344 CDD:278523 18/21 (86%)
C2H2 Zn finger 324..344 CDD:275368 16/19 (84%)
zf-H2C2_2 336..361 CDD:290200 19/24 (79%)
C2H2 Zn finger 352..372 CDD:275368 16/19 (84%)
osr2XP_005173612.1 COG5048 <55..>276 CDD:227381 139/221 (63%)
C2H2 Zn finger 136..156 CDD:275368 16/19 (84%)
zf-H2C2_2 148..173 CDD:290200 22/24 (92%)
C2H2 Zn finger 164..184 CDD:275368 18/19 (95%)
zf-H2C2_2 176..199 CDD:290200 21/22 (95%)
C2H2 Zn finger 192..212 CDD:275368 17/19 (89%)
zf-C2H2 218..240 CDD:278523 18/21 (86%)
C2H2 Zn finger 220..240 CDD:275368 16/19 (84%)
C2H2 Zn finger 248..268 CDD:275368 16/19 (84%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 53 1.000 Domainoid score I11342
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000748
OrthoInspector 1 1.000 - - mtm6437
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR14196
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2698
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
66.040

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