DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment bowl and cbt

DIOPT Version :9

Sequence 1:NP_001245861.1 Gene:bowl / 33602 FlyBaseID:FBgn0004893 Length:744 Species:Drosophila melanogaster
Sequence 2:NP_722636.1 Gene:cbt / 33224 FlyBaseID:FBgn0043364 Length:428 Species:Drosophila melanogaster


Alignment Length:341 Identity:86/341 - (25%)
Similarity:122/341 - (35%) Gaps:77/341 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 TESSSSEISGGGGGAIPMLRPSRMDQFMNSMA------------AAAAAVGGGGLPGAADRNGGS 55
            ||..:.||      |:|..:| |::|...||.            |...:|        ..|...|
  Fly    61 TEDEAPEI------AVPNKKP-RLEQPAMSMTPPPDQKLDDDQKAERVSV--------IMRVNSS 110

  Fly    56 GGSDGGSQNGNGDSRNSSASRISAYETQLAYQQHLAGLHGPPPPPPPSHHREISAFVPVLPTGKV 120
            |.....||:.|..|..|..|..|...|.                                 |..|
  Fly   111 GAVSSSSQDENSSSSTSCCSSSSNTNTS---------------------------------TSSV 142

  Fly   121 RPGSNSNYEIIAMMADKRKELALREAAAAAAMLGRGPGGPGGPGVPPPGVLYGPAGV----PPPP 181
            .|....:|....:..:.:.::..:.||..|....:.|..|....|.||    .||..    ...|
  Fly   143 PPTVEDDYPEANVWRNLKFKMNRKRAAEVALPPVQTPETPVAKLVTPP----APAECIKEEEIKP 203

  Fly   182 YLTGPGPSPTGAGS---FPFPPGAAAAALFPPGLGPGM-HAGLDRRLLRAPGRASRPKKQFICKF 242
            .||....||..:.:   ......||..:..|....|.| ...|..|:..|...|:| .:.:.|.|
  Fly   204 ILTPIYVSPVASSASQLILLSTVAAQQSPTPVPKTPTMSEEKLTTRITAAQAAATR-SRIYECSF 267

  Fly   243 --CNRQFTKSYNLLIHERTHTDERPYSC--DICGKAFRRQDHLRDHRYIHSKEKPFKCTECGKGF 303
              |.:.:.||.:|..|:|.||.|||:.|  :.|.|.|.|.|.|..|:..|:.||.|:|:.|.|.|
  Fly   268 PDCGKNYFKSSHLKAHQRVHTGERPFICKWENCDKRFSRSDELSRHKRTHTGEKKFQCSVCQKKF 332

  Fly   304 CQSRTLAVHKILHMEE 319
            .:|..|:.|...|.::
  Fly   333 MRSDHLSKHVKRHNKD 348

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
bowlNP_001245861.1 COG5048 <232..372 CDD:227381 34/92 (37%)
C2H2 Zn finger 240..260 CDD:275368 8/21 (38%)
zf-H2C2_2 252..277 CDD:290200 12/26 (46%)
C2H2 Zn finger 268..288 CDD:275368 8/21 (38%)
zf-H2C2_2 280..303 CDD:290200 9/22 (41%)
C2H2 Zn finger 296..316 CDD:275368 7/19 (37%)
zf-C2H2 322..344 CDD:278523
C2H2 Zn finger 324..344 CDD:275368
zf-H2C2_2 336..361 CDD:290200
C2H2 Zn finger 352..372 CDD:275368
cbtNP_722636.1 zf-C2H2 263..287 CDD:278523 8/23 (35%)
C2H2 Zn finger 265..287 CDD:275368 8/21 (38%)
COG5048 <270..362 CDD:227381 31/79 (39%)
zf-H2C2_2 279..306 CDD:290200 12/26 (46%)
C2H2 Zn finger 295..317 CDD:275368 8/21 (38%)
zf-H2C2_2 309..332 CDD:290200 9/22 (41%)
zf-C2H2 323..345 CDD:278523 8/21 (38%)
C2H2 Zn finger 325..345 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2698
SonicParanoid 00.000 Not matched by this tool.
11.030

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