DRSC/TRiP Functional Genomics Resources

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Protein Alignment bowl and egr1

DIOPT Version :9

Sequence 1:NP_001245861.1 Gene:bowl / 33602 FlyBaseID:FBgn0004893 Length:744 Species:Drosophila melanogaster
Sequence 2:NP_571323.1 Gene:egr1 / 30498 ZFINID:ZDB-GENE-980526-320 Length:511 Species:Danio rerio


Alignment Length:424 Identity:90/424 - (21%)
Similarity:137/424 - (32%) Gaps:157/424 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 FMNSMAAAAAAVGGGGLPGAA-DRNGGSGGSDGGSQNGNGDSRNSSASRISAYETQ----LAYQQ 88
            |:|: .|...||.|.|.||.. |...|...|:...:....|         ..|.||    ::|..
Zfish    45 FLNA-TAPEGAVFGSGEPGEQFDHLAGDTLSEISMEKPLSD---------QTYSTQRLPPISYTG 99

  Fly    89 H---------------------LAGLHGPPPPPPPSHHREISAFVPVLPTGKVRPGSNSNYEIIA 132
            .                     ::||.|..|||         |.:|...:....|.|:|...|.:
Zfish   100 RFTLEPATNCSNSLWAEPLFSLVSGLVGINPPP---------ASIPSSTSQATHPSSSSTSSIPS 155

  Fly   133 MMADKRKELALREAAAAAAMLGRGPGGPGGPGVPPPGVLYGPAGVPPPPYL---------TGPGP 188
            ..:......:|..:...:                .|..:|..|    |.|.         :||..
Zfish   156 SSSSSTSSASLSCSVHQS----------------EPNPIYSAA----PTYSSASPDIFPESGPNF 200

  Fly   189 SPT-------GAGSFP------------------FPPGAAAAALFPPGLGP-GMHAGLDRRL--- 224
            |.|       .:.::|                  |....:..:|.||...| ...||....|   
Zfish   201 STTVGTSLQYSSSTYPSAKTCNPSFSVPMIPDYLFTQQQSEISLVPPDQKPIQTQAGQQPALTPL 265

  Fly   225 --------------LRAPGRASRPKKQFICKFCNRQFTKSYNLLIHERTHTDERPYSCDI--CGK 273
                          |::..::...|...:.|:.||.          .:|...||||:|.:  |.:
Zfish   266 HTIKAFATQTGSQDLKSVYQSQLIKPSRMRKYPNRP----------SKTPPHERPYACPVETCDR 320

  Fly   274 AFRRQDHLRDHRYIHSKEKPFKCTECGKGFCQSRTLAVHKILHMEESPHKCPVCSRSFNQRSNLK 338
            .|.|.|.|..|..||:.:|||:|.                            :|.|:|::..:|.
Zfish   321 RFSRSDELTRHIRIHTGQKPFQCR----------------------------ICMRNFSRSDHLT 357

  Fly   339 THLLTHTDHKPYECSSCGKVFRRNCDLRRHALTH 372
            ||:.|||..||:.|..||:.|.|:.:.:||...|
Zfish   358 THIRTHTGEKPFACEICGRKFARSDERKRHTKIH 391

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
bowlNP_001245861.1 COG5048 <232..372 CDD:227381 40/141 (28%)
C2H2 Zn finger 240..260 CDD:275368 3/19 (16%)
zf-H2C2_2 252..277 CDD:290200 8/26 (31%)
C2H2 Zn finger 268..288 CDD:275368 7/21 (33%)
zf-H2C2_2 280..303 CDD:290200 8/22 (36%)
C2H2 Zn finger 296..316 CDD:275368 1/19 (5%)
zf-C2H2 322..344 CDD:278523 6/21 (29%)
C2H2 Zn finger 324..344 CDD:275368 6/19 (32%)
zf-H2C2_2 336..361 CDD:290200 12/24 (50%)
C2H2 Zn finger 352..372 CDD:275368 7/19 (37%)
egr1NP_571323.1 DUF3446 99..185 CDD:288757 17/114 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 133..169 7/35 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 291..312 7/30 (23%)
zf-C2H2 311..335 CDD:278523 8/23 (35%)
C2H2 Zn finger 313..335 CDD:275368 7/21 (33%)
zf-H2C2_2 327..352 CDD:290200 11/52 (21%)
C2H2 Zn finger 343..363 CDD:275368 7/47 (15%)
zf-H2C2_2 355..380 CDD:290200 12/24 (50%)
C2H2 Zn finger 371..391 CDD:275368 7/19 (37%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 384..406 3/8 (38%)
DUF3432 403..498 CDD:288743
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2698
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.940

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