DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bowl and odd-1

DIOPT Version :9

Sequence 1:	NP_001245861.1	Gene:	bowl / 33602	FlyBaseID:	FBgn0004893	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_498552.2	Gene:	odd-1 / 181893	WormBaseID:	WBGene00003845	Length:	242	Species:	Caenorhabditis elegans

Alignment Length:	148	Identity:	74/148 - (50%)
Similarity:	92/148 - (62%)	Gaps:	20/148 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 PSPTGAGSFPFPPGAA---------AAALF-----PPGLGPGMHAGLDRRLLRAPGRASRPKKQF 238
            |:|:.|.:...|....         .:.||     |..|.|..|...:..:.:      ||||:|
Worm    70 PTPSNASTSTIPAQMTNENVLHLQIQSQLFSNLGTPWFLNPEQHNKTNNAIRK------RPKKEF 128

  Fly   239 ICKFCNRQFTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDHRYIHSKEKPFKCTECGKGF 303
            |||:|.|.|||||||:|||||||:|||:.|:.|||:||||||||||:|||:||||.||..|||||
Worm   129 ICKYCARHFTKSYNLMIHERTHTNERPFHCETCGKSFRRQDHLRDHKYIHAKEKPHKCEICGKGF 193

  Fly   304 CQSRTLAVHKILHMEESP 321
            ||.|||.||:..|..:.|
Worm   194 CQLRTLNVHRSCHHVQEP 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bowl	NP_001245861.1	COG5048	<232..372	CDD:227381	64/90 (71%)
		C2H2 Zn finger	240..260	CDD:275368	15/19 (79%)
		zf-H2C2_2	252..277	CDD:290200	17/24 (71%)
		C2H2 Zn finger	268..288	CDD:275368	15/19 (79%)
		zf-H2C2_2	280..303	CDD:290200	17/22 (77%)
		C2H2 Zn finger	296..316	CDD:275368	13/19 (68%)
		zf-C2H2	322..344	CDD:278523	74/148 (50%)
		C2H2 Zn finger	324..344	CDD:275368
		zf-H2C2_2	336..361	CDD:290200
		C2H2 Zn finger	352..372	CDD:275368
odd-1	NP_498552.2	C2H2 Zn finger	130..150	CDD:275368	15/19 (79%)
		zf-H2C2_2	142..167	CDD:290200	17/24 (71%)
		C2H2 Zn finger	158..178	CDD:275368	15/19 (79%)
		zf-H2C2_2	170..193	CDD:290200	17/22 (77%)
		C2H2 Zn finger	186..206	CDD:275368	13/19 (68%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I7667
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000748
OrthoInspector	1	1.000	-	-		mtm4817
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14196
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.040