DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment bowl and Egr4

DIOPT Version :9

Sequence 1:NP_001245861.1 Gene:bowl / 33602 FlyBaseID:FBgn0004893 Length:744 Species:Drosophila melanogaster
Sequence 2:NP_065621.1 Gene:Egr4 / 13656 MGIID:99252 Length:478 Species:Mus musculus


Alignment Length:336 Identity:95/336 - (28%)
Similarity:126/336 - (37%) Gaps:90/336 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 PMLRPS-RMDQFMNSMAAAAAAVGG---------GGLPGAADRNGGSGGSDGGSQNGNGDSRNSS 73
            |.::|. |......::.|||:|..|         .|:||    |.||.||          .:.:.
Mouse   175 PDVKPGLRAPPASPALDAAASAFKGPYAPWELLSAGVPG----NCGSQGS----------FQTTP 225

  Fly    74 ASRISAYETQLAYQQHLAGLHGPPP-PPPPSHHREISAFVPVLPTGKVRPGSNSNYEIIAMMADK 137
            .:|.||..|::   :.|..:..|.. |.|.:...:..|:    .|..:.||.             
Mouse   226 EARFSAVGTKV---EDLLSISCPAELPGPAARLYQAGAY----DTFSLAPGD------------- 270

  Fly   138 RKELALREAAAAAAMLGRGPGGPGGPG-------VPPPGVLYGPAGV--------PPPPYLTGPG 187
                 |.|.......|...|||.||.|       ..||..| .|.|:        ..|.....||
Mouse   271 -----LGEGTEGLPALLTPPGGEGGSGGEGGEFLAAPPAQL-SPLGLRGAATADFSKPLVADLPG 329

  Fly   188 PSPTGAGSFPFPPGAAAAALFPPGLGPGMHAGLDRRLLRAPGRAS------RPK-KQFIC--KFC 243
            .|...|.|.|       ||.||        |...||..|..|:.|      ||. |.|.|  :.|
Mouse   330 GSGVAAPSSP-------AASFP--------AAKARRKGRRGGKCSARCFCPRPHVKAFACPVESC 379

  Fly   244 NRQFTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDHRYIHSKEKPFKCTECGKGFCQSRT 308
            .|.|.:|..|..|.|.||..:|:.|.||.:.|.|.|||..|...|:.||||.|..||:.|.:|..
Mouse   380 VRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSDE 444

  Fly   309 LAVHKILHMEE 319
            ...|..:|:::
Mouse   445 KKRHSKVHLKQ 455

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
bowlNP_001245861.1 COG5048 <232..372 CDD:227381 37/97 (38%)
C2H2 Zn finger 240..260 CDD:275368 8/21 (38%)
zf-H2C2_2 252..277 CDD:290200 10/24 (42%)
C2H2 Zn finger 268..288 CDD:275368 9/19 (47%)
zf-H2C2_2 280..303 CDD:290200 11/22 (50%)
C2H2 Zn finger 296..316 CDD:275368 6/19 (32%)
zf-C2H2 322..344 CDD:278523
C2H2 Zn finger 324..344 CDD:275368
zf-H2C2_2 336..361 CDD:290200
C2H2 Zn finger 352..372 CDD:275368
Egr4NP_065621.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 275..302 7/26 (27%)
zf-C2H2 372..396 CDD:278523 9/23 (39%)
C2H2 Zn finger 374..396 CDD:275368 8/21 (38%)
zf-H2C2_2 388..413 CDD:290200 10/24 (42%)
COG5048 400..>458 CDD:227381 22/56 (39%)
C2H2 Zn finger 404..424 CDD:275368 9/19 (47%)
zf-H2C2_2 416..441 CDD:290200 12/24 (50%)
C2H2 Zn finger 432..452 CDD:275368 6/19 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2698
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.940

Return to query results.
Submit another query.