DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bowl and osr2

DIOPT Version :9

Sequence 1:	NP_001245861.1	Gene:	bowl / 33602	FlyBaseID:	FBgn0004893	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	XP_002934454.1	Gene:	osr2 / 100038196	XenbaseID:	XB-GENE-481907	Length:	312	Species:	Xenopus tropicalis

Alignment Length:	180	Identity:	134/180 - (74%)
Similarity:	144/180 - (80%)	Gaps:	7/180 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   199 PPGAAAAALFPPGLGPGM----HAGLDRRLLRAPGR-ASRPKKQFICKFCNRQFTKSYNLLIHER 258
            ||.....:...||||..:    ....||:..|  || .|:.||:||||||.|.||||||||||||
Frog   130 PPKIGDLSKLSPGLGSPISEISKLSPDRKPSR--GRLPSKTKKEFICKFCGRHFTKSYNLLIHER 192

  Fly   259 THTDERPYSCDICGKAFRRQDHLRDHRYIHSKEKPFKCTECGKGFCQSRTLAVHKILHMEESPHK 323
            ||||||||:||||.||||||||||||||||||||||||.||||||||||||||||.|||:|||||
Frog   193 THTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHMQESPHK 257

  Fly   324 CPVCSRSFNQRSNLKTHLLTHTDHKPYECSSCGKVFRRNCDLRRHALTHA 373
            ||.|.|:||||||||||||||||.|||.|..||||||||||||||:|||:
Frog   258 CPTCGRTFNQRSNLKTHLLTHTDIKPYSCEQCGKVFRRNCDLRRHSLTHS 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bowl	NP_001245861.1	COG5048	<232..372	CDD:227381	121/139 (87%)
		C2H2 Zn finger	240..260	CDD:275368	17/19 (89%)
		zf-H2C2_2	252..277	CDD:290200	22/24 (92%)
		C2H2 Zn finger	268..288	CDD:275368	18/19 (95%)
		zf-H2C2_2	280..303	CDD:290200	21/22 (95%)
		C2H2 Zn finger	296..316	CDD:275368	17/19 (89%)
		zf-C2H2	322..344	CDD:278523	18/21 (86%)
		C2H2 Zn finger	324..344	CDD:275368	16/19 (84%)
		zf-H2C2_2	336..361	CDD:290200	20/24 (83%)
		C2H2 Zn finger	352..372	CDD:275368	16/19 (84%)
osr2	XP_002934454.1	C2H2 Zn finger	174..194	CDD:275368	17/19 (89%)
		zf-H2C2_2	186..211	CDD:372612	22/24 (92%)
		C2H2 Zn finger	202..222	CDD:275368	18/19 (95%)
		zf-H2C2_2	214..237	CDD:372612	21/22 (95%)
		C2H2 Zn finger	230..250	CDD:275368	17/19 (89%)
		COG5048	251..>312	CDD:227381	47/57 (82%)
		C2H2 Zn finger	258..278	CDD:275368	16/19 (84%)
		C2H2 Zn finger	286..306	CDD:275368	16/19 (84%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	53	1.000	Domainoid score	I11158
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000748
OrthoInspector	1	1.000	-	-		mtm9337
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.030