Protein Alignment CG43707 and BOI2

DIOPT Version :10

• Sequence 1: NP_001260005.1
• Gene: CG43707 / 33601
• FlyBaseID: FBgn0263846
• Length: 2021
• Species: Drosophila melanogaster
• Sequence 2: NP_011039.1
• Gene: BOI2 / 856850
• SGDID: S000000916
• Length: 1040
• Species: Saccharomyces cerevisiae
• Alignment Length: 1213
• Identity: 236/1213 - (19%)
• Similarity: 402/1213 - (33%)
• Gaps: 334/1213 - (27%)

  Fly   390 LSPRPPHRIKVVSQGAQ-TNGLQNGKKLTKSLSEIPNGKDGTSSHHYQQGSIYPHEMIYRTQSQD 453
            |..:|..:|||::...: .:|...|:.|..:                ::| :||   :..||...
Yeast    62 LDMKPGDKIKVITDDEEYKDGWYFGRNLRTN----------------EEG-LYP---VVFTQKIT 106

  Fly   454 VTPLQTLSDAQNNIMYYKP---PPPLLDAHSYGLGMEHLSRTRPSPSEQNVEYVNVNAAAVALNE 515
            |....||..|::....|.|   ..|||.:........:.....|.|.|        .||:::...
Yeast   107 VEKAPTLMRAKSTKRIYSPLTNEDPLLSSTFISENDSNSELPTPQPIE--------TAASISRTA 163

  Fly   516 SFDYESN-SLPRRACTSHTDFYSNSLPRRHITESSELMTDSVPLDFSQSHLLPPPSEYCKNDDED 579
            :...|.| ||            .|::        |::  |:..|:|....:.||        |..
Yeast   164 NGKIERNLSL------------KNTM--------SDI--DNALLEFKDDSIGPP--------DRF 198

  Fly   580 VEEYYDEDEDHPHET-----------ESYSSEVCMEQAAQHRRMSMLPQMIDSPFRRDDLRRQSM 633
            :....||:....|||           ||.|.........               |...||..|:.
Yeast   199 INSGRDEEHSITHETILSATDGLDVVESNSKPTTSSSTG---------------FLNGDLENQAT 248

  Fly   634 PVYG-QTEKLIDGFGP-RSSFRRRDKVSCFPDEPPAVQEVRDEQEIFIDFKPHISPKPSPKLQLK 696
            .:.| .|.||    .| .:.|...::::.:     .:.|..|.|......|..||.|...:|:|.
Yeast   249 LINGIDTTKL----NPVEAEFWSPEEITAY-----FIMEGYDVQSASRFQKHKISGKILLELELV 304

  Fly   697 HRKQHKAEIAMRKMQQQRMAQAAALTLPKPKSQPVEVEVRKVELEPSDEEEDEDEVSEPEEEDDG 761
            |.|:........:.:                   :..|:.|::
Yeast   305 HLKELDINSFGTRFE-------------------IFKEIEKIK---------------------- 328

  Fly   762 EEIDDDEQKLETDLQEDEEPLYENITPCGCRVVPTSDAEDIQDKRSQFRKRSVSLDDDYEAKASE 826
            |.|..:.:.|....:.:...:|.       :::|.::.:.....|...||.|.|| :|..::.:.
Yeast   329 EAIRTNGRSLNRASKTNNANIYN-------QLMPPANVDQRASYRGHVRKTSQSL-EDLPSQQNF 385

  Fly   827 TPTPTGLRLPST----PASPCRDELLANVSTYPS-------SDSLANDNTRDHSDGIWNESQVTV 880
            .|||...|..|.    |.|...|...||.:..|.       .:...|:|               :
Yeast   386 IPTPRNTRNSSASKHRPKSLVFDSQEANANIAPDVQIPQVVEEMAGNEN---------------L 435

  Fly   881 LTAEQRDISDGSYSSNLLLTPSSKRKNLLLQHQQRSSVDTDALDFEEQSPTYGLQTLPK---IIK 942
            ..:.:|.....||.|     |:...|:.||.:.:.|  .:.|..:..||||..... ||   .|.
Yeast   436 FVSPRRAPKPPSYPS-----PAQPPKSPLLNNTRTS--PSPAQLYSWQSPTLSFSG-PKRTSYID 492

  Fly   943 TPTPTTSRPTSTQPMMPPPAIAVTPSTNQILDSCISS-PLPKRSMVARGSVPDARQLMFTSGATK 1006
            ..:.:.|...|...:         |..||.....:|. |.|.|:.| |....:.:   .||.:.:
Yeast   493 QYSSSDSNFNSRSAL---------PKNNQGGGKALSPIPSPTRNSV-RNEDSEGK---LTSSSKR 544

  Fly  1007 QRHSDASFLPMGAADYARSADISECSTNTDEYATCTDTSKRTPVSTQSSQLEKTHAGSSFESASS 1071
            .......:.|..::|..     |.||::.:|....|..:...|.|            |.:...|:
Yeast   545 NSVPYYGYAPESSSDRK-----SSCSSHEEEQFQETMNTFERPTS------------SIYADGST 592

  Fly  1072 LYSMREDLLQHDEKERDKQTTLTKAQLKSPIGSVAELTRKSPSHSISSTTSSGSCPVLGAAIKSP 1136
            :.|:..|.|.| |||..|:.|...:.|.|...|.   :|::.|...||:.|..|.....:.:.||
Yeast   593 IASISNDKLAH-EKEGKKKPTRHSSSLSSKSKSD---SRRNSSLKRSSSASRTSSFKKSSFMLSP 653

  Fly  1137 AKESLPQTVASSVTSQMKVSSVECIP------PGVKPKPDSISEDERSEVRYSSSGYYESPHEED 1195
            .::......|.|  |..:.:.:..:|      |.|..|....|..:|..|....:..:....::|
Yeast   654 FRQQFTDNAARS--SSPEENPITSMPSEKNSSPIVDKKSSKKSRSKRRSVSAKEAEIFTETVKDD 716

  Fly  1196 DEE-------QGTRSKARRLRQEDER---KRRKTSMKLDIEKENMRALTSPIKKPTGSSKITSPE 1250
            ..:       :|...|.:.|||...|   |:::||..:    |.:|::         |.|....:
Yeast   717 KNKRSASEAIKGETLKGKSLRQMTARPVAKKKQTSAFI----EGLRSI---------SVKEAMKD 768

  Fly  1251 QSISGTMD---NGSSPSKMKRFRPKIRRQL---------RKSSREDVLAAAAV--RRSRATPTIF 1301
            ...||.|.   :|:..:...||......:|         |:....|:.|...|  :......:::
Yeast   769 ADFSGWMSKKGSGAMSTWKTRFFTLHGTRLSYFSSTTDTRERGLIDITAHRVVPAKEDDKLVSLY 833

  Fly  1302 GLSSGSGD--TELLLDASMSTGAVAGTT-TSAVTSVSAPSS--------ASKLPTSESSVTTQPE 1355
            ..|:|.|.  .:||   ....|:..|.| |...|...|..:        |:.:.|:....|:.|
Yeast   834 AASTGKGRYCFKLL---PPQPGSKKGLTFTQPRTHYFAVDNKEEMRGWMAALIKTTIDIDTSVP- 894

  Fly  1356 AVVAPLPAKKPHSCATPTSLLS------------PKLPTTSGTQSKSTSDTFQLKAKSIESLRSV 1408
             :::        |..|||..||            .||......:::...|.|....:.::.
Yeast   895 -IIS--------SYTTPTVSLSKAQEMLAEAREETKLREQQMLENEEDEDQFLWDQQQLQQ---- 946

  Fly  1409 SPGSDSVFYSEADGNAASGEQSHCHHCGKEMEGKQQSNTIS---------ELAGDSVESIPYIEQ 1464
                     .:.|.|....:::   ..........:.||||         ...|.:..|.|::..
Yeast   947 ---------QQHDNNQGQADRT---ISASTQRTSDEDNTISTPNLSSANNTTIGSNGFSSPFLLA 999

  Fly  1465 DIVKPPSDFADSPVTTKTTQRLYKKMDKRFRSEERYHGERGRH 1507
            ..:..|.      |...::.|..:|..| |.:||.|.|:..:|
Yeast  1000 SGLLSPG------VARNSSMRGTEKKGK-FSTEEDYFGDNSKH 1035

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43707	NP_001260005.1	PHA03369	<987..1394	CDD:223061	93/459 (20%)
		PDZ	1700..1776	CDD:214570
		PH-like	1792..1893	CDD:473070
		PH-like	1911..2011	CDD:473070
BOI2	NP_011039.1	SH3_BOI	47..101	CDD:212819	11/58 (19%)
		SAM_BOI-like_fungal	264..328	CDD:188934	14/87 (16%)
		PH_Boi	770..886	CDD:270126	23/118 (19%)