Protein Alignment CG43707 and BOI1

DIOPT Version :10

• Sequence 1: NP_001260005.1
• Gene: CG43707 / 33601
• FlyBaseID: FBgn0263846
• Length: 2021
• Species: Drosophila melanogaster
• Sequence 2: NP_009468.1
• Gene: BOI1 / 852193
• SGDID: S000000181
• Length: 980
• Species: Saccharomyces cerevisiae
• Alignment Length: 1007
• Identity: 198/1007 - (19%)
• Similarity: 344/1007 - (34%)
• Gaps: 273/1007 - (27%)

  Fly   636 YGQTEKLIDGFGPRSSFRRRDKV----SCFPDEPPAVQEVRD---EQEIFIDFKPHISPKPS-PK 692
            ||.........|..||.::.::.    |...|...|::|:|.   |||  :...|...|:.| |:
Yeast    98 YGNLNDSASNIGKVSSHQQENRYTSLKSTMSDIDKALEELRSGSVEQE--VSKSPTRVPEVSTPQ 160

  Fly   693 LQLKHRK-QHKAEIAMRKMQQQRMAQAAALTLPKPKSQPV-EVEVRKVELEPSDEEEDEDEVS-- 753
            ||.:... |.|.............:..|.|.|.....:.: :..:....||||.|...:.::.
Yeast   161 LQDEQTLIQEKTRNEENTTHDSLFSSTADLNLSSESLKNISKSNISTKSLEPSSESVRQLDLKMA 225

  Fly   754 ---EPEEEDDGEEIDDDEQK---------------LETDLQEDEEPLYENITPCGCRVVPTSDAE 800
               .|||..|...:...:|.               ||.:|:..:|   ..|...|.|.   ...:
Yeast   226 KSWSPEEVTDYFSLVGFDQSTCNKFKEHQVSGKILLELELEHLKE---LEINSFGIRF---QIFK 284

  Fly   801 DIQDKRSQFRKRSVSLDDDYEAKASETPTPTGLRLPSTPASPCRDELLANVSTYPSSDSLANDNT 865
            :|::.:|.....|..||.||...|.|  ......:|:  |:..|||:...:|      |..|..:
Yeast   285 EIRNIKSAIDSSSNKLDADYSTFAFE--NQAAQLMPA--ATVNRDEIQQQIS------SKCNKLS 339

  Fly   866 RDHSDGIWNESQVTVLTAEQRDISDGSYSSNLLLTPSSKRKNLLLQHQQRSSVDTDALDFEEQSP 930
            .:.||    ....:|.|..||       .|::::.|:.|      .|.....:    ||..|...
Yeast   340 SESSD----RKSSSVTTELQR-------PSSVVVNPNFK------LHDPAEQI----LDMTEVPN 383

  Fly   931 TYGLQTLPKIIKTPTPTTSRPTSTQPMMPPPAIAVTPS-TNQILDSCISSP-----LPKR---SM 986
            .:..:   .|.::|......|:...|:.||.    :|| .|:..::....|     .||.   ::
Yeast   384 LFADK---DIFESPGRAPKPPSYPSPVQPPQ----SPSFNNRYTNNNARFPPQTTYPPKNKNPTV 441

  Fly   987 VARGSVPDARQLMFTSGATKQRHSDASF-LP-MGAAD------YARSADISECST-NTDE----- 1037
            .:.|.:|::        :|...:|...| .| |...|      ...||.|...:| ||||
Yeast   442 YSNGLIPNS--------STSSDNSTGKFKFPAMNGHDSNSRKTTLTSATIPSINTVNTDESLPAI 498

  Fly  1038 -----YATCTDTSKRTPVSTQSSQLEKTHAGSSFESASSLYSMREDLLQHDEKERDKQ------T 1091
                 .||....::.:.|....   ::|.:||||....:..||...:....::|..||      .
Yeast   499 SNISSNATSHHPNRNSVVYNNH---KRTESGSSFVDLFNRISMLSPVKSSFDEEETKQPSKASRA 560

  Fly  1092 TLTKAQLKSPIG-----SVAELTRKSPSHSI-----SSTTSSGSCPVLGAAIKSPAK-------- 1138
            ....|:.||..|     |::|:.:...:.||     |.:.|:.:.|........|||
Yeast   561 VFDSARRKSSYGHSRDASLSEMKKHRRNSSILSFFSSKSQSNPTSPTKQTFTIDPAKMTSHSRSQ 625

  Fly  1139 -ESLPQTVASSVTSQMKVSSVECIPPGVKPKPDSISE-DERSEVRYSSSGYYESPHEEDDEE--- 1198
             .|.....:.|.:...|.|.|      ..|...|:|. :.:|.:..:.|   |:|...:::|
Yeast   626 SNSYSHARSQSYSHSRKHSLV------TSPLKTSLSPINSKSNIALAHS---ETPTSSNNKEAVS 681

  Fly  1199 QGTRSKARRLRQEDERKRRKTSMKLDIEKENMRALTSPIKKPTGSSKITSPEQSISGTMDNGSSP 1263
            |.:..|.:...:...:.:.|.|                      |||             :|||.
Yeast   682 QPSEGKHKHKHKHKSKHKHKNS----------------------SSK-------------DGSSE 711

  Fly  1264 SKMKRFRPKIRRQLRKSSREDVLAAAAVRRSRATPTIFGLSSGSGDTELLLDASMSTGAVAGTTT 1328
            .|.|       ::|..|::|..:.:...:||.:..|       ...|:.:|..|.:........|
Yeast   712 EKSK-------KKLFSSTKESFVGSKEFKRSPSELT-------QKSTKSILPRSNAKKQQTSAFT 762

  Fly  1329 SAVTSVSAPSSASKLPTSESSVTTQPEAVVAPLPAKKPHSCATPTSLLSPKLPTTSGTQSKSTSD 1393
            ..:.|::|..|   :.|::.|.....:...|....|:             :..|..||:....::
Yeast   763 EGIRSITAKES---MQTADCSGWMSKKGTGAMGTWKQ-------------RFFTLHGTRLSYFTN 811

  Fly  1394 TFQLKAKSIESLRS--VSPGSDS----VFYSEADGNAASGEQSHC-------------------- 1432
            |...|.:.:..:.:  |.|.||.    ..|:     |:.|:..:|
Yeast   812 TNDEKERGLIDITAHRVLPASDDDRLISLYA-----ASLGKGKYCFKLVPPQPGSKKGLTFTEPR 871

  Fly  1433 -HHCGKEMEGKQQS--NTISELAGDSVESIPYIEQDIVKPPSDFADSPVTTKTTQRLYK--KMDK 1492
             |:...|.:.:.::  :.|.:...|...|:|.|        |.:|...:.....|.|.:  ::..
Yeast   872 VHYFAVENKSEMKAWLSAIIKATIDIDTSVPVI--------SSYATPTIPLSKAQTLLEEARLQT 928

  Fly  1493 RFRSEERYHG-----------ERGRHYKTRQE 1513
            :.|..|...|           :|..:|...|:
Yeast   929 QLRDAEEEEGRDQFGWDDTQNKRNSNYPIEQD 960

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43707	NP_001260005.1	PHA03369	<987..1394	CDD:223061	88/454 (19%)
		PDZ	1700..1776	CDD:214570
		PH-like	1792..1893	CDD:473070
		PH-like	1911..2011	CDD:473070
BOI1	NP_009468.1	SH3_BOI	17..71	CDD:212819
		SAM_superfamily	226..290	CDD:472832	13/69 (19%)
		PH_Boi	778..894	CDD:270126	19/133 (14%)