Protein Alignment CG10019 and SLC16A4

DIOPT Version :10

• Sequence 1: NP_001368939.1
• Gene: CG10019 / 33600
• FlyBaseID: FBgn0031568
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_004687.1
• Gene: SLC16A4 / 9122
• HGNCID: 10925
• Length: 487
• Species: Homo sapiens
• Alignment Length: 492
• Identity: 101/492 - (20%)
• Similarity: 198/492 - (40%)
• Gaps: 77/492 - (15%)

  Fly   423 LRRTGVDTTRIRQYFYP-DGGWGWIICGVSFLVHILTTGLQLSYGLLWFYAVQYLHNTS-GIELL 485
            |:|.|    :::.|... ||||||:|....|||::...|:..::.:.:....:....|| .|..:
Human     2 LKREG----KVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWI 62

  Fly   486 GALSWSVSMVATSFVVSLCRKRSIRLLSIVGGLVMPLGILFTSFATEFGQVVFSYGIVFGVGVAM 550
            |::..|:...|...|..:|.....:..||:|..|:..|.|.:|:||....:..:.|::.|:|.|.
Human    63 GSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAF 127

  Fly   551 VREASTVMLGNYFKRRRQFVEMVAMSGEGVG--IALFSVILKEGVGKAGWRLGLQIVAALTALSF 613
            :.:.:.|:...|||:|......:|.||.|:.  :|.|:..|   :....|...|.:..|:.....
Human   128 LYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFL---IDLYDWTGALILFGAIALNLV 189

  Fly   614 FMGLMYRP-----------------ASLYHPQRRAIQ-HL------------------------- 635
            ...::.||                 .|.:.|:..|.: |.
Human   190 PSSMLLRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDSTTQKAGLPSKNLTV 254

  Fly   636 -KNQRKKM----REKKPILSQDVES------TPKYFFLDISSLKSVTVKILLMTSSVASFGIYTP 689
             :||.::.    ...:.:|..|.||      :.|..| |||..::....|...:..::....:.|
Human   255 SQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQLF-DISLFRNPFFYIFTWSFLLSQLAYFIP 318

  Fly   690 MFLMALNAAEQGSDVQELVLLQTFLGISMALGVVIAGALLRRCFVIRHFVINTKIVTQLFLSIVA 754
            .|.:...|...|.|:.:...|.:..||...:..:|:|.:..:.::.::....:.::.....:::|
Human   319 TFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQNWIKKYHYHKSYLILCGITNLLA 383

  Fly   755 LAILFLSFVMGYTGLCILSWLYGIGLGGFQYSLKILALERIKLKHFSKAWGFIRGVESVPVLISV 819
            ........:|.|| :|     :.|..||:...:..:.::..:....::..|.......:.||...
Human   384 PLATTFPLLMTYT-IC-----FAIFAGGYLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGP 442

  Fly   820 PLTSFLNDYSLKYGRAGYY--ICSAAAAISGIIIFFI 854
            |:..:|.||:..|..:.|:  ||...:::|   .||:
Human   443 PIAGWLYDYTQTYNGSFYFSGICYLLSSVS---FFFV 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10019	NP_001368939.1	MFS_MCT_SLC16	444..840	CDD:340910	88/454 (19%)
SLC16A4	NP_004687.1	MFS_MCT5	20..481	CDD:340979	93/470 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..250		4/43 (9%)