DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10019 and ESBP6

DIOPT Version :9

Sequence 1:	NP_001368939.1	Gene:	CG10019 / 33600	FlyBaseID:	FBgn0031568	Length:	1159	Species:	Drosophila melanogaster
Sequence 2:	NP_014274.1	Gene:	ESBP6 / 855598	SGDID:	S000005069	Length:	673	Species:	Saccharomyces cerevisiae

Alignment Length:	529	Identity:	115/529 - (21%)
Similarity:	205/529 - (38%)	Gaps:	98/529 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   385 PSLHATTPHPSHITDEEDSAFPGLA---DREFH--------LLHRNIPA--------LRRTGV-- 428
            |..|.||...| ::....|||...:   |...|        :.:|..||        |...|:
Yeast   120 PVTHTTTAGAS-LSAPSSSAFSASSIQNDTTEHKASMDSKLMRNRLYPASTKHSGKDLEAQGITE 183

  Fly   429 ---DTTRIRQYFY----------PDGGWGWIICGVSFLVHILTTGLQLSYGLLWFYAVQYL-HNT 479
               |...:::.|.          ||||:||::....||....|.|...|:|:...|   || |:|
Yeast   184 FEPDEPTVKKVFTNKSTGQLELPPDGGYGWVVTFCVFLTMFSTWGCNASFGVDLAY---YLNHDT 245

  Fly   480 ------SGIELLGALSWSVSMVATSFVVSLCRKRSIRLLSIVGGLVMPLGILFTSFATEFGQVVF 538
                  ....|:..|:..:..:.:..|::|.|...:|...:.|..||....|..||.|:..|:..
Yeast   246 YPGASKYDYALIAGLTVFLGQLLSPLVMALMRIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYV 310

  Fly   539 SYGIVFGVGVAMVREASTVMLGNYFKRRRQFVEMVAMSGEGVGIALFSVILKEGVGKAG-WRLGL 602
            :.|.:.|..::::...:|.:|..:|.::|.....|::.|.|.|..::.:...:.:...| .|..|
Yeast   311 TQGFMVGCSISLIFVPATTVLPGWFLKKRAVAMGVSLLGTGAGGVVYGLATNKMLSDFGNTRWCL 375

  Fly   603 QIVAALTALSFFMGLMYRPASLYHPQRRAIQHLKNQRKKMREKKPILSQDVESTPKYFFLDIS-- 665
            :|:....::|..:.:..                      ::|:.|..:..::| |:..|..:.
Yeast   376 RIIGISCSISVLVAIAL----------------------LKERNPTPAIGLKS-PRAMFEQLKAM 417

  Fly   666 -SLKSVT---VKILLMTSSVASFGIYTPMFLMALNAAEQGSDVQELVLLQTFLGISMALG---VV 723
             |||.:|   |.::.:....|.|.....:|.::..|..:|....:...|...|..|.::|   :.
Yeast   418 FSLKVITKPFVVLIALWFMFALFAYNMMVFTLSSYAISKGLSSHDASTLTAILNGSQSIGRPLMG 482

  Fly   724 IAGALLRRCFVIRHFVINTKIVTQLFLSIVALAILFLSFVMGYT--GLCILSWLYGIGLGGFQYS 786
            :||....|.        |..||....|:|    .:|..::..:|  .|...|.|.|..:|.....
Yeast   483 LAGDKFGRA--------NVTIVLTTLLTI----YMFAFWIPAHTFVQLIFFSILVGSCVGVANVM 535

  Fly   787 LKILALERIKLKHFSKAWGFIRGVESVPVLISVPLTSFL---NDYSLKYGRAGYYI-CSAAAAIS 847
            ..:|..:.:|.:.|..||.|:....:..:|:...:...|   .|.|..|..|..:. |...||:
Yeast   536 NTVLIADMVKPEEFLPAWAFVNYCGAPFLLVCEVIAQALTVEKDKSNPYLHAQIFCGCCFIAAL- 599

  Fly   848 GIIIFFISE 856
             |:|..:.|
Yeast   600 -ILISILRE 607

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10019	NP_001368939.1	MFS_MCT_SLC16	444..840	CDD:340910	88/418 (21%)
ESBP6	NP_014274.1	MFS_MCT_SLC16	212..606	CDD:340910	93/433 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010