Protein Alignment CG10019 and Slc16a3

DIOPT Version :10

• Sequence 1: NP_001368939.1
• Gene: CG10019 / 33600
• FlyBaseID: FBgn0031568
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_109621.1
• Gene: Slc16a3 / 80879
• MGIID: 1933438
• Length: 470
• Species: Mus musculus
• Alignment Length: 530
• Identity: 115/530 - (21%)
• Similarity: 196/530 - (36%)
• Gaps: 131/530 - (24%)

  Fly   439 PDGGWGW-------IICGVSF----LVHILTTGLQLSYGL-----LWFYAVQYLHNTSGIELLGA 487
            |||||||       ||.|.|:    .|.:....|...:|:     .|..::          ||..
Mouse    16 PDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELMHEFGIGYSDTAWISSI----------LLAM 70

  Fly   488 LSWSVSMVATSFVVSLCRKR-SIRLLSIVGGLVMPLGILFTSFATEFGQVVFSYGIVFGVGVAMV 551
            |      ..|..:.|:|..| ..|.:.:||||...||::..||.....|:..:.|::.|:|:|:.
Mouse    71 L------YGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLGLALN 129

  Fly   552 REASTVMLGNYFKRRRQFVEMVAMSGEGVGIALFSVILKEGVGKAGWRLGLQIVAALTALSFFMG 616
            .:.|.:||..||.:||.....:|.:|..|.:...|.:.:......|||.|..|:..|........
Mouse   130 FQPSLIMLNRYFNKRRPIANGLAAAGSPVFLCALSPLGQLLQDHYGWRGGFLILGGLLLNCCVCA 194

  Fly   617 LMYRPASLYHPQRRAIQHLKNQRKKMREKKPILSQDVESTPKYFFLDISSLKSVTVKILLMTSSV 681
            .:.||  |..||.......:..::                |....||:|..:.....|..:.:|:
Mouse   195 ALMRP--LVAPQVGGGTEPRGPQR----------------PPQRLLDLSVFRDRGFLIYAVAASI 241

  Fly   682 ASFGIYTPMFLMALNAAEQGSDVQELVLLQTFLGISMALGVVIAGALLRRCFVIRHFVINTKIVT 746
            ...|::.|...:...|.:.|....:...|.|.||.........||           |:...|.|.
Mouse   242 MVLGLFVPPVFVVSYAKDMGVPDTKAAFLLTILGFIDIFARPTAG-----------FITGLKKVR 295

  Fly   747 QLFLSIVALAILFLSF-------VMGYTGLCILSWLYGIG---LGGFQYSLKILALERIKLKHFS 801
            ...:.:.:.|:.|..|       ...|.||.:....:||.   :|..|:.: ::|:  :..:.||
Mouse   296 PYSVYLFSFAMFFNGFTDLTGSTATDYGGLVVFCIFFGISYGMVGALQFEV-LMAI--VGTQKFS 357

  Fly   802 KAWGFIRGVESVPVLISVPLTSFLNDYSLKYGRAGYYICSAAAAISGIII----FF--------- 853
            .|.|.:..:|:|.|||..|....|.|.:..| :..:.:..|....|.:::    ||
Mouse   358 SAIGLVLLLEAVAVLIGPPSGGKLLDATKVY-KYVFILAGAEVLTSSLVLLLGNFFCIGKRKRPE 421

  Fly   854 ISEPQQQHQQQQQQLHHHYQQRNGHLATPTLMRHASARQHRPHLPMDYGYGEYPAPDLLSRSCIS 918
            ::||::...::                          :.|:|  |:|.|              :.
Mouse   422 VTEPEEVASEE--------------------------KLHKP--PVDVG--------------VD 444

  Fly   919 LNQMEPYLQA 928
            ..::|.:|:|
Mouse   445 SREVEHFLKA 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10019	NP_001368939.1	MFS_MCT_SLC16	444..840	CDD:340910	96/422 (23%)
Slc16a3	NP_109621.1	MFS_MCT3_4	21..410	CDD:340988	98/437 (22%)
		Basolateral sorting signal. /evidence=ECO:0000250|UniProtKB:O15427	429..446		5/58 (9%)
		Basolateral sorting signal. /evidence=ECO:0000250|UniProtKB:O15427	446..470		3/9 (33%)