DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10019 and slc16a5b

DIOPT Version :9

Sequence 1:	NP_001368939.1	Gene:	CG10019 / 33600	FlyBaseID:	FBgn0031568	Length:	1159	Species:	Drosophila melanogaster
Sequence 2:	XP_001919658.1	Gene:	slc16a5b / 794371	ZFINID:	ZDB-GENE-131120-181	Length:	547	Species:	Danio rerio

Alignment Length:	617	Identity:	134/617 - (21%)
Similarity:	234/617 - (37%)	Gaps:	135/617 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   350 HQPPPTQQQQHHHQQRAKNLMANGGCYFGYEANHHPSLHATTPHPSHITDEEDSAFPGLADREFH 414
            |||.|.....   :.||.:|.|       :|.....|..:..|......::..|..|    .|.|
Zfish     8 HQPQPNTTVT---RSRASSLQA-------FENADTASCKSEEPDQEEEEEQSSSTLP----EERH 58

  Fly   415 LLHRNIPALRRTGVDTTRIRQYFYPDGGWGWIICGVSFLVHILTTGLQLSYGLLWFYA-VQYLHN 478
            .         .||   .:......|||||||::...:.||..:|.......|:  ||. :|....
Zfish    59 C---------STG---GQANAQLAPDGGWGWVVVAATILVLAMTLAFPSCIGI--FYTELQSDFQ 109

  Fly   479 TSGIELLGALSWSVSMVAT---------SFVVSLCRKRSIRLLSIVGGLVMPLGILFTSFATEFG 534
            .|..|    .||..:::..         |.:|..|   ..|...|:||::..||:..:|||....
Zfish   110 ASNTE----TSWVPAIMMAVLHACGPICSVLVERC---GCRATIIIGGILSGLGMAASSFAQTMV 167

  Fly   535 QVVFSYGIVFGVGVAMVREASTVMLGNYFKRRRQFVEMVAMSGEGVGIALFSVILKEGVGKAGWR 599
            ::..:.||:.|:|.::..:.|..|:|:||.|||.|...::.:|..:|:::..::....:...|||
Zfish   168 ELYITAGIITGMGFSLCFQPSITMVGHYFVRRRAFANALSSTGTALGLSILPLLANYLLRNFGWR 232

  Fly   600 LGLQIVAALTALSFFMGLMYRP-ASLYHPQRRAIQ----HLK------NQRKKMREKKPI----- 648
            ....::..:.......|.:.|| |:....:.|..:    |||      :|..|.|.:..:
Zfish   233 GSFLVLGGVLLNCCVCGAVMRPLAAKPKTETRTKETDNHHLKTNCLSVHQGLKGRLRATLSTIMT 297

  Fly   649 -----LSQDVESTPKYF---FLDISSLKSVTVKILLMTSSVASFGIYTPMFLMALNAAEQGSDVQ 705
                 ::.|:..:..||   .|.:|.:               ..|...|:..:...|...|.:..
Zfish   298 FLRRHMAFDLLCSNPYFCAYALGVSWM---------------MLGFVVPLVYLVPYATAYGMEQD 347

  Fly   706 ELVLLQTFLGISMALGVVIAGALLRRCFVIRHFVINTKIVTQL----------FLSIVALAILFL 760
            :..||...||:   :.:::..|              |.||..|          :|..:|:.|..|
Zfish   348 QAALLMAILGL---INIIVRPA--------------TAIVFGLPRFRGSHNFAYLFAIAVVINGL 395

  Fly   761 SFVMGYTGLCILSWLYGIGLGGFQYSLK-----ILALERIKLKHFSKAWGFIRGVESVPVLISVP 820
            |..:...|...|..|..:.|.||..||.     .:.::.:::..|..|.|.|..:||:.:|:..|
Zfish   396 SNCVCGIGTSFLVLLVYVILFGFSMSLVGSLLFTVLMDTVEMSRFPSALGLISIMESIMLLLGPP 460

  Fly   821 LTSFLNDYSLKYGRAGYYICSAAAAISGIII---FFISEPQQQHQQQQQQLHHHYQQRNGHLATP 882
            |...|.|.:.:|... ::.||...:.:|:.|   |:..:.::..:|.:....|    ::.|...|
Zfish   461 LAGILVDSTGQYIYV-FFACSVTGSTAGLFIMLSFYWLDRRRDREQVKSSSAH----QDPHSLKP 520

  Fly   883 TLMRHASARQHRPHLPMDYGYGEYPAPDLLSR 914
            :|           .:.:|..|...|.....||
Zfish   521 SL-----------KMTIDCEYSPVPLHSKNSR 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10019	NP_001368939.1	MFS_MCT_SLC16	444..840	CDD:340910	97/444 (22%)
slc16a5b	XP_001919658.1	2A0111	71..511	CDD:331689	108/481 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920