Protein Alignment CG10019 and SLC16A1

DIOPT Version :10

• Sequence 1: NP_001368939.1
• Gene: CG10019 / 33600
• FlyBaseID: FBgn0031568
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_003042.3
• Gene: SLC16A1 / 6566
• HGNCID: 10922
• Length: 500
• Species: Homo sapiens
• Alignment Length: 485
• Identity: 116/485 - (23%)
• Similarity: 201/485 - (41%)
• Gaps: 89/485 - (18%)

  Fly   436 YFYPDGGWGWIICGVSFLVHILTTGLQLSYGL-----LWFYAVQYLHNTSGIELLGALSW-SVSM 494
            |..|||||||.:...:|:      .:..||..     ::|..::.:.:.:..|    :|| |..|
Human    11 YTPPDGGWGWAVVIGAFI------SIGFSYAFPKSITVFFKEIEGIFHATTSE----VSWISSIM 65

  Fly   495 VATSF----VVS-LCRKRSIRLLSIVGGLVMPLGILFTSFATEFGQVVFSYGIVFGVGVAMVREA 554
            :|..:    :.| |..|...|::.||||.:...|::..||.....|:....|::.|:|:|.....
Human    66 LAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNP 130

  Fly   555 STVMLGNYFKRRRQFVEMVAMSGEGVGIALFSVILKEGVGKAGWRLGLQIVAALTALSFFMGLMY 619
            :..|:|.||.:||.....:||:|..|.:...:.:.:...|..|||....|:..|.......|.:.
Human   131 ALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGALM 195

  Fly   620 RP--------------ASLYHPQRRAIQ---HLKNQ----RKKMREKKPILSQDVESTPKYFFLD 663
            ||              |||....:..::   |..|.    |...:||:.:. |.:..     |||
Human   196 RPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVF-QTINQ-----FLD 254

  Fly   664 ISSLKSVTVKILLMTSSVASFGIYTPM-FLMALNAAEQGSDVQELVLLQTFLGISM----ALGVV 723
            ::........:.|..:.:..||::.|: ||.:...::..|..:...||.....:.|    ::|:
Human   255 LTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVARPSMGL- 318

  Fly   724 IAGALLRRCFVIRHFVINTKIV---TQLFL--SIVALAILFLSFVMG--YTGLCILSWLYGIGLG 781
                           |.|||.:   .|.|.  |:||..:..:...:.  |.|.|:.:..:|...|
Human   319 ---------------VANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFG 368

  Fly   782 GFQYSLKILALERIKLKHFSKAWGFIRGVESVPVLISVPLTSFLNDYSLKYG--RAGYYICSAAA 844
            .....|....::.:..:.||.|.|.:..||..|||:..||...|||   .||  :..|:.|....
Human   369 WLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLND---MYGDYKYTYWACGVVL 430

  Fly   845 AISGIIIF--------FISEPQQQHQQQQQ 866
            .||||.:|        .:::.|:.::|:::
Human   431 IISGIYLFIGMGINYRLLAKEQKANEQKKE 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10019	NP_001368939.1	MFS_MCT_SLC16	444..840	CDD:340910	102/441 (23%)
SLC16A1	NP_003042.3	2A0113	1..455	CDD:273325	115/478 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	454..500		1/7 (14%)