DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10019 and Slc16a8

DIOPT Version :9

Sequence 1:	NP_001368939.1	Gene:	CG10019 / 33600	FlyBaseID:	FBgn0031568	Length:	1159	Species:	Drosophila melanogaster
Sequence 2:	NP_065262.1	Gene:	Slc16a8 / 57274	MGIID:	1929519	Length:	492	Species:	Mus musculus

Alignment Length:	444	Identity:	107/444 - (24%)
Similarity:	181/444 - (40%)	Gaps:	84/444 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   439 PDGGWGWIICGVSFLVHILTTGLQLSYGL----------------------LWFYAVQ--YLHNT 479
            |||||||::.|..|:|    ||  .:||.                      .|..::.  .|:.|
Mouse    13 PDGGWGWVVLGACFVV----TG--FAYGFPKAVSVFFRELKRDFGAGYSDTAWVSSIMLAMLYGT 71

  Fly   480 SGIELLGALSWSVSMVATSFVVSLCRKRSIRLLSIVGGLVMPLGILFTSFATEFGQVVFSYGIVF 544
                  |.||   |::.|.|        ..|.:.:.|||:...|::..|||:...::..:.|::.
Mouse    72 ------GPLS---SILVTRF--------GCRPVMLAGGLLASAGMILASFASRLVELYLTAGVLT 119

  Fly   545 GVGVAMVREASTVMLGNYFKRRRQFVEMVAMSGEGVGIALFSVILKEGVGKAGWRLGLQIVAALT 609
            |:|:|:..:.|.:|||.||:|||.....:|.:|..|.:::.|.:.:....:.|||.|..:...|.
Mouse   120 GLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSMLSPLGQLLGERFGWRGGFLLFGGLL 184

  Fly   610 ALSFFMGLMYRPASLYHPQRRAIQHLKNQRKKMREKKPILSQDVESTPKYFFLDISSLKSVTVKI 674
            ......|.:.||.....|:|....|....|::.                  .||::........:
Mouse   185 LHCCACGAVMRPPPGPPPRRDPSPHGGPARRRR------------------LLDVAVCTDRAFVV 231

  Fly   675 LLMTSSVASFGIYTPMFLMALNAAEQGSDVQELVLLQTFLGISMALGVVIAGALLRRCFVIRHFV 739
            .::|..:.:.|::.|..|:...|.:.|....|...|.:.:|....:.....|||.....:..|
Mouse   232 YVVTKFLMALGLFVPAILLVNYAKDAGVPDAEAAFLLSIVGFVDIVARPACGALAGLGRLRPH-- 294

  Fly   740 INTKIVTQLF-LSIVA--LAILFLSFVMGY---TGLCILSWL-YGIGLGGFQYSLKILALERIKL 797
                 |..|| |:::|  |..|..:....|   ...||...| ||: :|..|:.   :.:..:..
Mouse   295 -----VPYLFSLALLANGLTDLISARARSYGTLVAFCIAFGLSYGM-VGALQFE---VLMATVGA 350

  Fly   798 KHFSKAWGFIRGVESVPVLISVPLTSFLNDYSLKYGRAGYYICSAAAAISGIII 851
            ..|..|.|.:..||:|.|||..|....|.| :||.....:|:..:..|::|:.:
Mouse   351 PRFPSALGLVLLVEAVAVLIGPPSAGRLVD-ALKNYEIIFYLAGSEVALAGVFM 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10019	NP_001368939.1	MFS_MCT_SLC16	444..840	CDD:340910	100/426 (23%)
Slc16a8	NP_065262.1	2A0113	14..440	CDD:273325	106/443 (24%)
Slc16a8	NP_065262.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	419..492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I9079
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920