DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10019 and kar

DIOPT Version :9

Sequence 1:	NP_001368939.1	Gene:	CG10019 / 33600	FlyBaseID:	FBgn0031568	Length:	1159	Species:	Drosophila melanogaster
Sequence 2:	NP_001189213.1	Gene:	kar / 45883	FlyBaseID:	FBgn0001296	Length:	612	Species:	Drosophila melanogaster

Alignment Length:	526	Identity:	121/526 - (23%)
Similarity:	210/526 - (39%)	Gaps:	89/526 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   439 PDGG-WGWIICGVSFLVHILTTGLQLSYGLLWFYAVQYL------HNTSGIELLGALSWSVSMVA 496
            |||| ..|::...:||.:.:..|...:||::.......|      ..:|...|:|||:...:.:.
  Fly    74 PDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGTTFLF 138

  Fly   497 TSFVVSLCRKRSIRLLSIVGGLVMPLGILFTSFATE-FGQVVFSYGIVFGVGVAMVREASTVMLG 560
            ::....|..|..:||.:..||::...|:|.:||.|| .|.:.|:|||:||:|.|:....:..:||
  Fly   139 STMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTLAILG 203

  Fly   561 NYFKRRRQFVEMVAMSGEGVGIALFSVILKEGVGKAGWRLGLQIVAALTALSFFMGLMYRPASLY 625
            :||||....|.....:|..|...:....|.:.:|..|....|:|::.::|.......:|:|   .
  Fly   204 HYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKP---L 265

  Fly   626 HPQRRAIQHLKNQRKKMREKKPILSQDVESTPKYFFLDISSLKSVTVKILLMTSSVASFGIYTPM 690
            ||...     ..::|..|.:..:..:.:        :::...|.....|..:...:|.||.:.|.
  Fly   266 HPPPE-----PPKKKPGRSRINLFLRSI--------INVEIWKRKRFVIWALCVPLALFGYFVPY 317

  Fly   691 --FLMALNAAEQGSDVQELVLLQTFLGISMALGVVIAGALLRRCFVIRHFV-INTKIVTQLFLSI 752
              .:..:.....|.||...|:.   :||:..:|.:|.|       ||.... :|...:.||.|..
  Fly   318 VHMMQFVKTTFPGEDVNLPVMC---IGITSGIGRLIFG-------VIADMPGVNRMYLQQLSLVS 372

  Fly   753 VALAILFLSFVMGYTGLCILSWLYGIGLGGFQYSLKILALERIKLKHFSKAWGFIRGVESVPVLI 817
            :.|..|.|.....|..|...:.:.|:..|.|...|..:|.|.......::|.||:.|:.|:|:.:
  Fly   373 IGLVTLLLPLTNSYVILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIGFLLGLSSIPLTV 437

  Fly   818 SVPLTSFL----NDYSLKYGRAGYYICSAAAAISGIIIFFISEPQQQHQQQQQQL---------- 868
            ..|:...:    |.|:|....||     ....:...::|.|...:::........
  Fly   438 GPPVAGMIFDSTNSYTLPLILAG-----LPPLLGSSLLFLIKCVKEEENGVSAPRAVVLANGDIE 497

  Fly   869 ---HHHYQQR---------------NGHL-ATPTLMRHASARQHRPHLPMDYGYGEY-----PAP 909
               :.||:..               ||.. |:||:       |...|  :|.|.|.|     |:|
  Fly   498 IAGNGHYRSAGTKSSAPLMGATNGINGSAPASPTI-------QSNGH--VDNGTGSYPDSPWPSP 553

  Fly   910 DLLSRS 915
            ..:|.|
  Fly   554 TRISDS 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10019	NP_001368939.1	MFS_MCT_SLC16	444..840	CDD:340910	98/409 (24%)
kar	NP_001189213.1	MFS	81..459	CDD:119392	96/403 (24%)
kar	NP_001189213.1	MFS_1	124..439	CDD:284993	84/340 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020