Protein Alignment CG10019 and LOC4578143

DIOPT Version :10

• Sequence 1: NP_001368939.1
• Gene: CG10019 / 33600
• FlyBaseID: FBgn0031568
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: XP_061518930.1
• Gene: LOC4578143 / 4578143
• VectorBaseID: AGAMI1_011088
• Length: 951
• Species: Anopheles gambiae
• Alignment Length: 1062
• Identity: 401/1062 - (37%)
• Similarity: 530/1062 - (49%)
• Gaps: 289/1062 - (27%)

  Fly   274 GAVGSGMP-------------------------SVMPAPPPPRYANPNINGCCYMYNPMPPAHQS 313
            |.||.|.|                         |..|.|.||....|..|||......|..|:.:
Mosquito     3 GLVGDGKPRLGSDDPLHDDDDLDDDPNADSPALSASPPPAPPPLPPPVRNGCQRCRFSMASANST 67

  Fly   314 -HHQHDH---------------------HHA-----QQHHPVAQHQHHPHQYGPQYCLCDNWYHQ 351
             :..|.|                     |..     :::| :|....|.|..|....:...
Mosquito    68 LNRSHPHLASGTGTLGSGSVGSGTLPRAHRGGGGTLERNH-MAASSGHLHTAGVTATVASG---- 127

  Fly   352 PPPTQQQQHHHQQRAKNLMANGGCYFGYEANHHPSLHATTPHPSHITDEEDSAFPGLADREFHLL 416
                               |..|.|.||:.|             .:.||||||:|.|.:||.|.|
Mosquito   128 -------------------AGNGTYPGYDRN-------------RLLDEEDSAYPALLERELHSL 160

  Fly   417 HRNIPALRRTGVDTTRIRQYFYPDGGWGWIICGVSFLVHILTTGLQLSYGLLWFYAVQYLHNTSG 481
            |||:|||||.|||||.|||:||||||||||:|||:||.|:||||.|||||||..||:::|.:...
Mosquito   161 HRNVPALRRAGVDTTAIRQHFYPDGGWGWIVCGVAFLAHVLTTGFQLSYGLLLLYAIRHLGHEVN 225

  Fly   482 IEL--LGALSWSVSMVATSFVVSLCRKRSIRLLSIVGGLVMPLGILFTSFATEFGQVVFSYGIVF 544
            .|.  ||..||::|:.:.:.||:|||::|.||.:::||||:.||||||||||:..||.||||::.
Mosquito   226 TEAGWLGPASWAMSLFSATIVVALCRRKSTRLTAVLGGLVLALGILFTSFATQLHQVAFSYGVIV 290

  Fly   545 GVGVAMVREASTVMLGNYFKRRRQFVEMVAMSGEGVGIALFSVILKEGVGKAGWRLGLQIVAALT 609
            |:|.|||||::.||||:|||||||||||:.|||||||:|||||||||||||.|||||||.|..|.
Mosquito   291 GIGSAMVRESAAVMLGHYFKRRRQFVEMITMSGEGVGVALFSVILKEGVGKMGWRLGLQAVTGLV 355

  Fly   610 ALSFFMGLMYRPASLYHPQRRAIQHLKNQRKKMREKKPILSQDVESTPKYFFLDISSLKSVTVKI 674
            :.||||||:||||||||||||||.||||||||::|||..:     .|||..|||.:.|||.:|::
Mosquito   356 SFSFFMGLLYRPASLYHPQRRAILHLKNQRKKVKEKKTHV-----RTPKPPFLDFTPLKSSSVRM 415

  Fly   675 LLMTSSVASFGIYTPMFLMALNAAEQGSDVQELVLLQTFLGISMALGVVIAGALLRRCFVI--RH 737
            |.:::|||:.|||:|:|.::|:...:|.|:|:|||||||||:|:|||:|.:|:.:.:...|  |.
Mosquito   416 LSISASVAALGIYSPIFFLSLHGFSEGYDMQDLVLLQTFLGLSIALGIVFSGSSINKTLEISFRK 480

  Fly   738 FVINTKIVTQLFLSIVALAILFLSFVMGYTGLCILSWLYGIGLGGFQYSLKILALERIKLKHFSK 802
            ..|:.:.|.|..:::|::::|.||.|..|.|||..:|.||:||||::|:||:||:|||:.|:|||
Mosquito   481 VQISRQYVCQGCVTLVSVSLLVLSAVADYRGLCFSAWAYGLGLGGYRYTLKMLAIERIRGKYFSK 545

  Fly   803 AWGFIRGVESVPVLISVPLTSFLNDYSLKYGRAGYYICSAAAAISGIIIFFISEPQQQHQQQQQQ 867
            |||||:|.||:|||..|||.:||||.|.:|||||||||:|:||||.||:||:..|..::.:
Mosquito   546 AWGFIKGAESLPVLFGVPLCAFLNDSSHRYGRAGYYICAASAAISAIILFFVGYPDGRNMK---- 606

  Fly   868 LHHHYQQRNGHLAT----PT--------LMRHASARQHRPHLPMDY--------------GYGEY 906
                 ...||.:.:    ||        |.|..|::::..:....|              |.|.|
Mosquito   607 -----YSTNGSITSRCTAPTSSSDCQHILDRSFSSQRYNNNPQQWYSGNTHATNLSNGCHGSGSY 666

  Fly   907 PAPDLLSRSCISLNQ------------MEPYLQANFCQR------HMLQQQQQQQQQQQHSHLQQ 953
            |....|.| |:|.:|            :.|...|.....      .:|...|
Mosquito   667 PGGPSLQR-CLSTSQFMNGGLNLSSGGIGPNSTATTAATAPGTGGRLLGNSQ------------- 717

  Fly   954 LACHNLDLQPHQGREAYQLGQGS--------------IGAKMGK---RLQRSLSFIQQHSNCCDG 1001
                :||...:.|    |||.|:              .|...|:   ||.:||||..|.....|.
Mosquito   718 ----SLDNPTNNG----QLGGGAGSAGGTGFSYHSPFCGQGAGQPHGRLHKSLSFAFQTPMFSDD 774

  Fly  1002 QMY--CSWHSTYELGCHKSNKNPGSADRQP-----LICTCSSPN-RNPVTYGTHGPT-------- 1050
            .::  |...|.|            :||..|     ..|...:|: ..|||  .|..|
Mosquito   775 PIHHTCQQASGY------------AADYPPPSRCYSRCELHNPSLATPVT--VHRDTLNRQHSFR 825

  Fly  1051 -GPPGPTGPPGPPSSTRSRSVPEGLSTMSQQCNCRQGPATFAAPTREFIYVPHAYASLQRTPHRH 1114
             ...|.|     |..|.:.:     |:.:||      |.|   |.....:.|..|.. |:.||:|
Mosquito   826 ASSRGQT-----PRHTSAHA-----SSRTQQ------PLT---PHHANHHHPPQYHP-QQQPHQH 870

  Fly  1115 SQ----------------------------------GAGSGPGPGNSALRNNPQCRLKRSQ---- 1141
            .|                                  |.|..||.|      .|.|......
Mosquito   871 QQQPQHHHQHHHQQQLPPYPANGLQYHPSRSRSVPEGLGVQPGAG------GPDCHWNHCHWTTA 929

  Fly  1142 ---SLCRPN-AVQFVEQITTSV 1159
               :.|||| .:|.||||||||
Mosquito   930 NGVNFCRPNRPIQVVEQITTSV 951

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10019	NP_001368939.1	MFS_MCT_SLC16	444..840	CDD:340910	236/399 (59%)
LOC4578143	XP_061518930.1	None