Protein Alignment CG10019 and SLC16A12

DIOPT Version :10

• Sequence 1: NP_001368939.1
• Gene: CG10019 / 33600
• FlyBaseID: FBgn0031568
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_998771.3
• Gene: SLC16A12 / 387700
• HGNCID: 23094
• Length: 516
• Species: Homo sapiens
• Alignment Length: 566
• Identity: 125/566 - (22%)
• Similarity: 223/566 - (39%)
• Gaps: 115/566 - (20%)

  Fly   392 PHPSHITDEEDSAF------PGLADREFHLLHRNIPALRRTGVDTTRIRQYFYPDGGWGWIICGV 450
            |..||.|.......      ||..::            |:|.....|.|....|||||||:|...
Human     2 PSGSHWTANSSKIITWLLEQPGKEEK------------RKTMAKVNRARSTSPPDGGWGWMIVAG 54

  Fly   451 SFLVHILTTGLQLSYGLLW-----FYAVQYLHNTSGIELLGALSWSVSMVATSFVVSLC------ 504
            .|||.|.|..:.....:.:     ::...|...          :|..|:|  ..|..||
Human    55 CFLVTICTRAVTRCISIFFVEFQTYFTQDYAQT----------AWIHSIV--DCVTMLCAPLGSV 107

  Fly   505 --RKRSIRLLSIVGGLVMPLGILFTSFATEFGQVVFSYGIVFGVGVAMVREASTVMLGNYFKRRR 567
              ...|.::..::|||:...|::.:||||....:..:.|::.|:|.|:....:..|:|.||.||:
Human   108 VSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRK 172

  Fly   568 QFVEMVAMSGEGVGIALFSVILKEGVGKAGWRLGLQIVAALTALSFFMGLMYRPASLYH----PQ 628
            .....:||||.|:|..:.:.:::..:.:..||..|.|:..........|.:.||.:|..    |:
Human   173 ALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDHTTPE 237

  Fly   629 RRAIQHLKNQRKKMREKKPI--LSQDVEST-------PKYFFLDISSLKSVTVKILLMTSSVASF 684
            :..:  .:.|::.::...|.  |:::...|       .:|.||.:|....:.|.:|.|....:..
Human   238 QNHV--CRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPL 300

  Fly   685 GIYTPMFLMALNAAEQGSDVQELVLLQTFLGISMALGVVIAGALL-RRCFVIRHFVINTKIVTQL 748
            .:|...:.:::     |...|:...|.:.||:...:|.:..|.|. |||      :.|.:.|..|
Human   301 FVYLVPYALSV-----GVSHQQAAFLMSILGVIDIIGNITFGWLTDRRC------LKNYQYVCYL 354

  Fly   749 FLSIVALAILFLSFVMGYTGLCIL--------------SWLYGIGLGGFQYSLKILALERIKLKH 799
                         |.:|..|||.|              |..:|...|.:...:.::..|.:....
Human   355 -------------FAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEIVGTTS 406

  Fly   800 FSKAWGFIRGVESVPVLISVPLTSFLNDYSLKYGRAGYYICSAAAAISGIIIFFISEPQQQHQQQ 864
            .|.|.|.:..:.:||.|:|.|:...|.|.:..| .|.:.:|..:...|.:::.|....::..:.|
Human   407 LSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSY-TAAFLLCGFSMIFSSVLLGFARLIKRMRKTQ 470

  Fly   865 QQQLHHHYQQR-----NGHLATPTLMRHASARQHRPHLPMDYGYGE 905
            .|.:......:     ||.:|      ::.||:      :|..:||
Human   471 LQFIAKESDPKLQLWTNGSVA------YSVARE------LDQKHGE 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10019	NP_001368939.1	MFS_MCT_SLC16	444..840	CDD:340910	97/436 (22%)
SLC16A12	NP_998771.3	MFS_MCT12	48..461	CDD:340982	100/451 (22%)