DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10019 and CG8051

DIOPT Version :9

Sequence 1:	NP_001368939.1	Gene:	CG10019 / 33600	FlyBaseID:	FBgn0031568	Length:	1159	Species:	Drosophila melanogaster
Sequence 2:	NP_001285434.1	Gene:	CG8051 / 32925	FlyBaseID:	FBgn0031012	Length:	616	Species:	Drosophila melanogaster

Alignment Length:	556	Identity:	114/556 - (20%)
Similarity:	199/556 - (35%)	Gaps:	183/556 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   418 RNIPALRRTGVDTTRIRQYFY-PDGGWGWII---CGVSFLVHILTTGLQLSYGLLWFYAVQYLHN 478
            :.:||.::.  |.:.:.:.|. |||||||::   .||:.||   |..|...:|:|:...:..| .
  Fly    60 QKVPAKKKR--DKSDLGEDFVAPDGGWGWLVSVASGVNILV---TFALAQQFGILFRDRMAGL-G 118

  Fly   479 TSGIELLGALSWSVSMVATSFVVS--LCRKRSIRLLSIVGGLVMPLGILFTSFATEFGQVVFSYG 541
            .|..||...::..:::.|.:.:::  |.|:.:.|::::||.::..||:.:..||..|...:.|:.
  Fly   119 ISSSELTTIINTQIAVSAFTGLLNGPLFRRYTYRVVALVGSVLTFLGLFWMVFADTFAVYIMSFS 183

  Fly   542 IVFGVGVAMVREASTVMLGNYF--KRRRQFVEMVAMSGEG------------------------V 580
            |::|.|..:...||::.:..||  |||........::|.|                        .
  Fly   184 ILYGFGRGLTVSASSLAVNTYFKVKRRTATAFQFGVAGLGPIVCPYFATYMLYEFGVQGTTLLFA 248

  Fly   581 GIALFSV--------------------------------------ILKEGV---------GKAGW 598
            |.:|.::                                      |:|..|         ...||
  Fly   249 GASLHTIACSLIYQPVKWHVVKRDRDAEALQQVQPLAEREDQDEDIIKNVVEPETPVLPRANDGW 313

  Fly   599 ---RLGLQIVAALTALSFF--------------------MGLMYRPASLYHPQR----------R 630
               |..|..|.....|:.:                    .|...|..|:.|..:          .
  Fly   314 FGSRASLNSVGTRNRLNTWEKSDSNGHVELKRLSSKDSNPGRQLRSISVSHSIKEEEATGYNSDH 378

  Fly   631 AIQH----------LKNQRKKMREKKPILSQDVESTPKY----FFLDISSLKSVT-----VKILL 676
            .:||          |::::::.|.||         .|.|    .|.|:..|:.:|     |.|.|
  Fly   379 EVQHTELTEKEKQELEDEKERQRRKK---------LPFYMKVVIFFDMDLLRDITYVNLAVGITL 434

  Fly   677 MTSSVASFGIYTPMFLMALNAAEQGSDVQELVLLQTFLGISMALGVVIAGALLRRCFVIRHFV-- 739
            :.....:|.|.||..|     ::.|.:..::.|..:.||..              ..|:|..:
  Fly   435 INFVEINFAILTPFIL-----SDLGFNKDQIALAMSTLGFF--------------DLVVRFLIPL 480

  Fly   740 ----INTKIVTQLFLSIVALAI--LFLSFVMG-YTGLCILSWLYGIGLG-GFQ---YSLKILALE 793
                ||....|...:.|:.:.|  :|||.... |..:.|..||   ||. .|:   :||.|.:.
  Fly   481 ITAKINLSNRTFFVVGILGMCIGRMFLSMTSNFYVMMAIFLWL---GLNKAFRTVFWSLIIPSY- 541

  Fly   794 RIKLKHFSKAWGFIRGVESVPVLISVPLTSFLNDYS 829
             :.||....|.|....:.....:|..||...:.|::
  Fly   542 -VPLKRLPAAAGLQLLMSGTFSMIFGPLIGLIRDHT 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10019	NP_001368939.1	MFS_MCT_SLC16	444..840	CDD:340910	105/529 (20%)
CG8051	NP_001285434.1	MFS	86..>266	CDD:119392	39/183 (21%)
		MFS	<428..598	CDD:119392	40/173 (23%)
		MFS_1	440..>572	CDD:284993	36/155 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020