DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10019 and Slc16a12

DIOPT Version :9

Sequence 1:	NP_001368939.1	Gene:	CG10019 / 33600	FlyBaseID:	FBgn0031568	Length:	1159	Species:	Drosophila melanogaster
Sequence 2:	NP_001178566.1	Gene:	Slc16a12 / 309525	RGDID:	1311468	Length:	486	Species:	Rattus norvegicus

Alignment Length:	489	Identity:	115/489 - (23%)
Similarity:	202/489 - (41%)	Gaps:	66/489 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   431 TRIRQYFYPDGGWGWIICGVSFLVHILTTGLQLSYGLLW-----FYAVQYLHNTSGIELLGALSW 490
            ||:.....|||||||:|....|||.|.|..:.....:.:     ::|..|          ...:|
  Rat     5 TRVGSASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDY----------SQTAW 59

  Fly   491 SVSMVATSFVVSLC--------RKRSIRLLSIVGGLVMPLGILFTSFATEFGQVVFSYGIVFGVG 547
            ..|:|  ..:..||        .:.|.:...::|||:...|::..||||....:..|.|::.|:|
  Rat    60 IHSIV--DCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGLILGSFATSLKHLYLSLGVLTGLG 122

  Fly   548 VAMVREASTVMLGNYFKRRRQFVEMVAMSGEGVGIALFSVILKEGVGKAGWRLGLQIVAALTALS 612
            .|:....:..|:|.||.||:.|...:||||.|:|..:.:.:::..:.:..||..|.|:.......
  Rat   123 FALCYSPAIAMVGKYFSRRKAFAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNL 187

  Fly   613 FFMGLMYRPASLYH-PQRRAIQHLKN-QRKKMREKKPILSQDVESTPK---------YFFLDISS 666
            ...|.:.||.:|.. |......|.:: ||:..::..|......|.|..         |.||.:|.
  Rat   188 CVCGALMRPITLKEDPSGPEKSHDRDAQREDCKQASPYSPLTKEWTETRLCCSLQQGYGFLLMSD 252

  Fly   667 LKSVTVKILLMTSSVASFGIYTPMFLMALNAAEQGSDVQELVLLQTFLGISMALGVVIAGALL-R 730
            ...:.|.:|.|....:...:|...:.:::     |....:...|.:.||:...:|.:..|.|. |
  Rat   253 FVVLAVSVLFMAYGCSPLFVYLVPYALSV-----GVSHHQAAFLMSILGVIDIVGNITFGWLTDR 312

  Fly   731 RCFVIRHFVINTKIVTQLF-LSIVALAILFLSFVMGYTGLCILSWLYGIGLGGFQYSLKILALER 794
            ||      :.|.:.|..|| :::..|..|.|..:..:..|...|..:|...|.:...:.::..|.
  Rat   313 RC------LKNYRYVCYLFAVALDGLCYLCLPMLQSFPLLVPFSCTFGYFDGAYVTLIPVVTAEI 371

  Fly   795 IKLKHFSKAWGFIRGVESVPVLISVPLTSFLNDYSLKYGRAGYYICSAAAAISGIIIFFISEPQQ 859
            :.....|.|.|.:..:.:||.|:|.|:..:|.|.:..| .|.:.:|..|...|.|::.|....::
  Rat   372 VGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSY-TAAFLLCGFAMIFSSILLGFAKIAKR 435

  Fly   860 QHQQQQQQLHHHYQQRNGHLATPTLMRHASARQH 893
            ..:.|                .|.|::.:..:.|
  Rat   436 MKRTQ----------------VPFLVKDSDPKLH 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10019	NP_001368939.1	MFS_MCT_SLC16	444..840	CDD:340910	99/421 (24%)
Slc16a12	NP_001178566.1	2A0111	12..451	CDD:331689	112/478 (23%)
Slc16a12	NP_001178566.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	201..221		4/19 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920