DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10019 and Slc16a7

DIOPT Version :9

Sequence 1:	NP_001368939.1	Gene:	CG10019 / 33600	FlyBaseID:	FBgn0031568	Length:	1159	Species:	Drosophila melanogaster
Sequence 2:	NP_001345425.1	Gene:	Slc16a7 / 20503	MGIID:	1330284	Length:	484	Species:	Mus musculus

Alignment Length:	434	Identity:	105/434 - (24%)
Similarity:	175/434 - (40%)	Gaps:	55/434 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   439 PDGGWGWIICGVSFLVHILTTGLQLSYGL-----LWFYAVQYLHNTSGIELLGALSW-SVSMVAT 497
            |||||||::...||:      .:..||..     ::|..:|.:.||:..:    ::| |..|:|.
Mouse    15 PDGGWGWVVVCASFI------SIGFSYAFPKAVTVFFKDIQEIFNTTSSQ----IAWISSIMLAV 69

  Fly   498 SFV---VS--LCRKRSIRLLSIVGGLVMPLGILFTSFATEFGQVVFSYGIVFGVGVAMVREASTV 557
            .:.   :|  |......|.:.|||||:..:|::..|::....::..:.|.:.|:|:|...:.:..
Mouse    70 MYAGGPISSVLVNNYGSRPVVIVGGLLCCIGMILASYSNSVIELYLTVGFIGGLGLAFNLQPALT 134

  Fly   558 MLGNYFKRRRQFVEMVAMSGEGVGIALFSVILKEGVGKAGWRLGLQIVAALTALSFFMGLMYRPA 622
            ::|.||.|||......||:|..|.::..:...:......||:....|:..:...|...|.:.||.
Mouse   135 IIGKYFYRRRPLANGCAMAGSPVFLSTLAPFNQYLFNNYGWKGSFLILGGIFLHSCVAGCLMRPV 199

  Fly   623 SLYHPQRRAIQHLKNQRKKM--REKKPILSQDVESTPKYF--FLDISSLKSVTVKILLMTSSVAS 683
            .   |.    .:.|..:.|:  |....:......||.:..  |||.|........|.|..:.:..
Mouse   200 G---PS----PNTKKSKSKVGSRHDSTLKKASKVSTAQKVNRFLDFSLFMHRGFLIYLSGNVILF 257

  Fly   684 FGIYTPMFLMALNAAEQG-SDVQELVLLQTFLGISM----ALGVVIAGALLRRCFVIRHFVINTK 743
            .||:.|:..:|..|...| .|.....||.....|.|    ::|::...:|:|            .
Mouse   258 LGIFAPIIFLAQYAKHIGVDDYNSAFLLSVMAFIDMFARPSVGLIANTSLIR------------P 310

  Fly   744 IVTQLFLSIV---ALAILFLSFVMGYTGLCILSWLYGIGLGGFQYSLKILALERIKLKHFSKAWG 805
            .:..||.|.:   .:..|.......|:.|.:....:|:|.|.....|....::.:....||.|.|
Mouse   311 RIQYLFSSAIIFTGICHLLCPLATTYSALVVYVVFFGLGFGSISSLLFECLMDIVGATRFSSAVG 375

  Fly   806 FIRGVESVPVLISVPLTSFLNDYSLKYGRAGYYICSAAAA-ISG 848
            ....||..|||...||...|.|.:.:|  ...||.|.... :||
Mouse   376 LTTIVECCPVLFGPPLAGKLLDITGEY--KYLYIASGTVVLVSG 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10019	NP_001368939.1	MFS_MCT_SLC16	444..840	CDD:340910	96/418 (23%)
Slc16a7	NP_001345425.1	2A0113	5..431	CDD:273325	105/434 (24%)
Slc16a7	NP_001345425.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	438..484
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I9079
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920