Protein Alignment CG10019 and mct-4

DIOPT Version :10

• Sequence 1: NP_001368939.1
• Gene: CG10019 / 33600
• FlyBaseID: FBgn0031568
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_001041267.1
• Gene: mct-4 / 180766
• WormBaseID: WBGene00003986
• Length: 777
• Species: Caenorhabditis elegans
• Alignment Length: 736
• Identity: 115/736 - (15%)
• Similarity: 227/736 - (30%)
• Gaps: 274/736 - (37%)

  Fly   439 PDGGWGWIICGVSFLVHILTTGLQLSYG-LLWFYAVQYLHNTSGIELLGALSWSVSMVATSFVVS 502
            ||||:||:|...:|:.:::..|:..::. ....|..:|..:......:|:|.....::....|.:
 Worm    70 PDGGYGWVIVFAAFMSNLVVDGISTAFSEFKQSYKERYQESDGLTVFIGSLIIGTYLLVGPLVSA 134

  Fly   503 LCRKRSIRLLSIVGGLVMPLGILFTSFATEFGQVVFSYGIVFGVGVAMVREASTVMLGNYFKRRR 567
            ||.|...|.:.:.|||:..:..:....:......:..||::.|:|..|:...:.|::|.||..:|
 Worm   135 LCNKYEQRYVVMAGGLISGIAFMIAPASPNIYVFMLIYGVMGGLGFGMIYLPAIVVVGFYFDSKR 199

  Fly   568 QFVEMVAMSGEGVGIALFSVILKEGVGKAGWRLGLQIVAALTALSFFMGLMYRPASLY------- 625
            .....::::|.|||..|..:|.:..:...||:..:.::|.:.....|.|.:|||..:.
 Worm   200 AMATGISVAGSGVGTFLVPLICQVCIANLGWQKTIWVLAVMIFSCVFYGYLYRPLPMVDLNEIRD 264

  Fly   626 ------------------------HPQRR------------------------------------ 630
                                    ||.|.
 Worm   265 QEMEPLRQALSKVEDDEDEAVESPHPNRSTSAASGAIEDEAVSQNPEVQRLRSILTEGDEGSETP 329

  Fly   631 ----------------------------------------------------------------- 630
                                                                             
 Worm   330 KSDAHKVRSHTATRSRKHTMTSNSGSQHDLKLSRGNLSSDNRLSRVSARDFNQSLSKLSKSGGAS 394

  Fly   631 ---------------------------AIQHLKN------------------------------- 637
                                       :||:||.
 Worm   395 NLSIAMSGVDPKEFQRPMNRQDIFYGGSIQNLKEFKEEGTMAGYRASTLSIPRSVVGQAVSQLNL 459

  Fly   638 QRKKMREKKPILSQDVESTPKYF-------------------FLDISSLKSVTVKILLMTSSVAS 683
            .|...|...|.:::|.|...:.|                   .:|::.||:.|:.||.:::.:..
 Worm   460 SRTGSRLGGPGIAEDEEEMIEPFVDDGCCKVLPLPMRNALSEMIDLNLLKNKTMMILCISNLLGM 524

  Fly   684 FGIYTP-MFLMALNAAEQGSDVQELVLLQTFLGISMALGVVIAGALLRRCFVIRHFVINTKIVTQ 747
            .|.|.| |||..|:.:.: .|:...:.|....|:...:|.|..|      ::....:::...:..
 Worm   525 MGFYIPIMFLKDLSESMK-LDMSLAMFLVPIFGVFNTIGRVFFG------WLTDQKILSALTINN 582

  Fly   748 LFLSIVALAILFLSFVMGYTGLCILSWLYGIGLGGFQYSLKILALERIKLKHFSKAWGFI---RG 809
            |.|.:..|..|....:....|....:.::|..:..:.....|:..:.:.|::.:.::|.:   ||
 Worm   583 LSLIVSGLLTLACPLLTSIAGQYFYAIVFGFIISAYICLTSIVLADLMGLENLTNSFGLLVVARG 647

  Fly   810 VESVPVLISVPLTSFLNDYSLKYGRAGYY---ICSAAAAISGIIIFFISE--------PQQQHQQ 863
            :.|   |:..|....:.|.:..|..|.|:   :...|..||..|.|...:        ||.|.|.
 Worm   648 IAS---LVGPPFAGIVYDITGSYDTAFYFGGLVLLVAGLISATIPFVTKKDADTADGMPQLQDQD 709

  Fly   864 QQQQLHHHYQQRNGHLATPTLMRHASARQHRPHLPMDYGYGEYPAPDLLSRSCISLNQMEPYLQA 928
            ..          :|.|:.                             |..||..:|...:..:|:
 Worm   710 NV----------SGKLSV-----------------------------LTERSEEALTDYQRTIQS 735

  Fly   929 NFCQRHMLQQQQQQQQQQQHS 949
            ...|..:||..::::::|:.:
 Worm   736 MKQQHQLLQDLEEEKRKQKQN 756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10019	NP_001368939.1	MFS_MCT_SLC16	444..840	CDD:340910	91/612 (15%)
mct-4	NP_001041267.1	MFS_MCT_SLC16	75..>252	CDD:340910	38/176 (22%)
		MFS	<507..689	CDD:475125	39/191 (20%)