DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10019 and Slc16a10

DIOPT Version :9

Sequence 1:	NP_001368939.1	Gene:	CG10019 / 33600	FlyBaseID:	FBgn0031568	Length:	1159	Species:	Drosophila melanogaster
Sequence 2:	NP_620186.1	Gene:	Slc16a10 / 170566	RGDID:	69197	Length:	514	Species:	Rattus norvegicus

Alignment Length:	458	Identity:	103/458 - (22%)
Similarity:	199/458 - (43%)	Gaps:	70/458 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   439 PDGGWGWIICGVSFLVHILTTGLQLSYGLLWFYAVQYLHNTSGIELLGA---------LSW--SV 492
            |:|||||::...:...:....|:|.:||:|:         .|.:|..||         .:|  |:
  Rat    64 PEGGWGWLVMLAAMWCNGSVFGIQNAYGVLF---------VSMLETFGAKDDDNMAFKAAWVGSL 119

  Fly   493 SMVATSF---VVSL------CRKRSIRLLSIVGGLVMPLGILFTSFATEFGQVVFSYGIVFGVGV 548
            ||....|   :||:      ||:     .:::|..|..:|::.:||.:....:.|:||:||..|.
  Rat   120 SMGMIFFCCPIVSVFTDMFGCRR-----TAVLGAAVGFVGLMSSSFVSSIEPLYFTYGVVFACGC 179

  Fly   549 AMVREASTVMLGNYFKRRRQFVEMVAMSGEGVGIALFSVILKEGVGKAGWRLGLQIVAALTALSF 613
            :...:.|.|:||:|||:|...|..:..:|..|...|..::|.......|....|:|:.....:.|
  Rat   180 SFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLTSTVGLCYTLRILCIFMFVLF 244

  Fly   614 FMGLMYRPASLYHPQRRAIQHLKNQRKKMRE--KKPILSQDVESTPKYFFLDISSLKSVTVKILL 676
            ..|..|||.            :.:.::|..|  :....|:...|.||..| :.:..|.....:..
  Rat   245 LAGFTYRPL------------VPSSKEKESEDSRSSFFSRRKLSPPKKIF-NFALFKETAYAVWA 296

  Fly   677 MTSSVASFGIYTPMFLMALNAAEQGSDVQELVLLQTFLGISMALGVVIAGAL------LRRCFVI 735
            ....:|.||.:.|...:..:..|:..||....:|...:|::..:|.::.|.:      :::.::
  Rat   297 AGIPLALFGYFVPYVHLMNHVKERFKDVNNKEVLFMCIGVTSGVGRLLFGRIADYLPGVKKVYL- 360

  Fly   736 RHFVINTKIVTQLFLSIVALAILFLSFVMGYTGLCILSWLYGIGLGGFQYSLKILALERIKLKHF 800
                   ::::..|:.:.::.|...|.......||::..|:.   |.|...:..:|.|.:..:..
  Rat   361 -------QVLSFFFIGLTSMMIPLCSVFGALIALCLIMGLFD---GCFISIMAPIAFELVGPQDA 415

  Fly   801 SKAWGFIRGVESVPVLISVPLTSFLNDYSLKYGRAGYYICSAAAAISGIIIFFISEPQQQHQQQQ 865
            |:|.||:.|..|:|:.:..|:...|:|....|..| :|:......|.|.::..|   ...|.::|
  Rat   416 SQAIGFLLGFMSIPMTVGPPVAGLLHDKLGSYDLA-FYLAGIPPFIGGAVLCLI---PWIHSKKQ 476

  Fly   866 QQL 868
            :::
  Rat   477 REI 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10019	NP_001368939.1	MFS_MCT_SLC16	444..840	CDD:340910	94/423 (22%)
Slc16a10	NP_620186.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..64		103/458 (22%)
		2A0113	60..481	CDD:273325	103/458 (22%)
		MFS	70..469	CDD:119392	96/440 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020