| Sequence 1: | NP_001137782.1 | Gene: | Shaw / 33599 | FlyBaseID: | FBgn0003386 | Length: | 619 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_004691.2 | Gene: | KCNQ4 / 9132 | HGNCID: | 6298 | Length: | 695 | Species: | Homo sapiens |
| Alignment Length: | 427 | Identity: | 99/427 - (23%) |
|---|---|---|---|
| Similarity: | 160/427 - (37%) | Gaps: | 130/427 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 161 YKGTISWWQEM--KPRIWSLFDEPYSSNAAKTIGVVSVF-----FIC--ISILSFCLKTHPDMRV 216
Fly 217 PIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISS---------PNKW 272
Fly 273 EFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTF 337
Fly 338 RASAKELTLLVFFLVLGIVIFAS-LVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPK 401
Fly 402 TYIGMFVGALCALAGVLTIALPVPVIVSNFAM---------------------------YYSHTQ 439
Fly 440 ARAK-----------LPKKRRRVL--------------PVEQPRQPRLPGAPG---GVSGCGTPG 476
Fly 477 SGP----HSGPMG-----SGGTGPRRMNNKTKDLVSP 504 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Shaw | NP_001137782.1 | BTB | 27..125 | CDD:197585 | |
| BTB_2 | 27..117 | CDD:280393 | |||
| Ion_trans | 244..439 | CDD:278921 | 58/231 (25%) | ||
| Ion_trans_2 | 355..429 | CDD:285168 | 32/74 (43%) | ||
| KCNQ4 | NP_004691.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..21 | ||
| MIG-14_Wnt-bd | <92..190 | CDD:284153 | 24/140 (17%) | ||
| Ion_trans | 126..330 | CDD:278921 | 57/235 (24%) | ||
| Ion_trans_2 | 246..320 | CDD:285168 | 32/76 (42%) | ||
| Selectivity filter. /evidence=ECO:0000250 | 283..288 | 3/4 (75%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 400..480 | 18/60 (30%) | |||
| KCNQ_channel | 474..653 | CDD:281513 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 496..515 | ||||
| A-domain (Tetramerization) | 546..650 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 587..606 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG2126 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||