Protein Alignment Shaw and kcnq1.2

DIOPT Version :9

• Sequence 1: NP_001137782.1
• Gene: Shaw / 33599
• FlyBaseID: FBgn0003386
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: XP_017209602.2
• Gene: kcnq1.2 / 796289
• ZFINID: ZDB-GENE-130530-935
• Length: 597
• Species: Danio rerio
• Alignment Length: 321
• Identity: 73/321 - (22%)
• Similarity: 139/321 - (43%)
• Gaps: 58/321 - (18%)

  Fly   245 AFFYIECVCNAWFTFEILVR---------FISSPNKWEFIKSSVNIIDYIATLSFYIDLVL---- 296
            :.|::|.|...:|..|.:||         ::....:..||:..::|||.|..::..:.|.:
Zfish   165 SLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGIKGRLRFIRKPISIIDLIVVVASVVVLSVGSNG 229

  Fly   297 QRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASL 361
            |.||:     ..:.....::|:|:..:.|.....::|........:||...::...||::..:..
Zfish   230 QVFAT-----SAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYF 289

  Fly   362 VYYAER--IQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPV 424
            ||.||:  :.......|:|....|||.:||:||:||||..|:|:||..:.:..::..:...|||.
Zfish   290 VYLAEKDAVDEEGKTGFSSYADALWWGVVTVTTIGYGDKVPQTWIGKAIASCFSVFAISFFALPA 354

  Fly   425 PVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGAPGGVS------GCGTPGS------ 477
            .::.|.||:         |:.:|:|     ::....::|.|...:.      .|....|
Zfish   355 GILGSGFAL---------KVQQKQR-----QKHFNRQIPAAASLIQTLWRCYACEKSDSCTATWK 405

  Fly   478 -----GPHSGPMGSGGTGP---RRMNNKTKDLVSPKSVAQLFA-GPLGASIVAMSPRTMLD 529
                 |.:...:.|..:.|   ||::.:.|.  .|||:....: ||.|...::: |:...|
Zfish   406 MYVLTGDYIPIINSENSSPGNFRRLSKRYKR--KPKSLRDNGSLGPAGERALSI-PQITYD 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585
		BTB_2	27..117	CDD:280393
		Ion_trans	244..439	CDD:278921	52/208 (25%)
		Ion_trans_2	355..429	CDD:285168	24/75 (32%)
kcnq1.2	XP_017209602.2	Ion_trans	133..369	CDD:306908	53/217 (24%)
		KCNQ_channel	487..>597	CDD:308886

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910