Protein Alignment Shaw and kcna6a

DIOPT Version :10

• Sequence 1: NP_001137782.1
• Gene: Shaw / 33599
• FlyBaseID: FBgn0003386
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_001124098.1
• Gene: kcna6a / 795490
• ZFINID: ZDB-GENE-080722-21
• Length: 475
• Species: Danio rerio
• Alignment Length: 452
• Identity: 168/452 - (37%)
• Similarity: 246/452 - (54%)
• Gaps: 73/452 - (16%)

  Fly    13 HAAM--NLINMDSENR-----VVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFF 70
            |.|:  ::..|:..::     |.:|:.|:|.||...||.:.|.|.|....:.:..:||:.||:||
Zfish    12 HVALLQDICEMEQSDQECCELVTINISGLRFETQLKTLARYPNTLLGDPIKRMRFFDPLRNEFFF 76

  Fly    71 DRHPGVFAQVLNYYRT-GKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAV 134
            ||:...|..:|.||:: |:|..|.:|...:|.:|::|:.:..:.:         :|....|.|..
Zfish    77 DRNRPSFDAILYYYQSGGRLRRPINVPVDMFLDEIKFYEIGDDVI---------KHFQEDEGLLK 132

  Fly   135 LDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFI 199
            .|...|    ||                      .|.|.:||.||:.|.||.||:.|.:|||..|
Zfish   133 EDERPL----PS----------------------NEFKRQIWLLFEHPDSSGAARIIAIVSVMVI 171

  Fly   200 CISILSFCLKTHPDMR---------VPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNA 255
            .|||:.||::|.|:.|         :|.....:|:..:.    :.|        .||.:|.:|..
Zfish   172 LISIIIFCIETLPEFREDDRVFDNHLPANSTTSVQRLSA----YTD--------PFFLLETICIV 224

  Fly   256 WFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVL-----QRFASHLENADILEFFSII 315
            ||.||:.:||::.|:|..|.|..:|.||.:|.:.::|.|.|     |.......:..||....::
Zfish   225 WFCFELFIRFLACPSKPTFFKDIMNTIDIVAIMPYFITLSLELGEVQSNQQQTTSLAILRVIRLV 289

  Fly   316 RIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIP 380
            |:.|:|||:|||.||:||.||.|||.:||.||:|||::||::|:|.||:||  ..:|...|.|||
Zfish   290 RVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLIIGIILFSSAVYFAE--ADDPETSFTSIP 352

  Fly   381 LGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYY--SHTQA 440
            ...|||:|:|||||||||.|.|..|..||::||:|||||||||||||||||..:|  .|.:|
Zfish   353 DAFWWAVVSMTTVGYGDMYPVTIGGKIVGSMCAIAGVLTIALPVPVIVSNFNYFYHREHNEA 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB_Shaw-like	24..135	CDD:349723	33/116 (28%)
		Ion_trans	188..439	CDD:459842	117/266 (44%)
		PRK14959	<418..>585	CDD:184923	17/25 (68%)
kcna6a	NP_001124098.1	BTB_POZ	31..157	CDD:453885	44/160 (28%)
		Ion_trans	203..411	CDD:459842	101/221 (46%)