DRSC/TRiP Functional Genomics Resources

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Protein Alignment Shaw and Kcnv1

DIOPT Version :9

Sequence 1:NP_001137782.1 Gene:Shaw / 33599 FlyBaseID:FBgn0003386 Length:619 Species:Drosophila melanogaster
Sequence 2:NP_080476.2 Gene:Kcnv1 / 67498 MGIID:1914748 Length:503 Species:Mus musculus


Alignment Length:432 Identity:145/432 - (33%)
Similarity:228/432 - (52%) Gaps:64/432 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 LNVGGIRHETYKATLKKIPATRLSRLTEALANY-------------------DPILNEYFFDRHP 74
            :||||.|....:..|...|.|||.:|...:|:|                   :|:.|||||||..
Mouse    46 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRLGALAAAPSPLELCDDANPVDNEYFFDRSS 110

  Fly    75 GVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLD 139
            ..|..||:|||||:||....:|...|.:|:::||:|...::.||...|.:.::..|||..  :.|
Mouse   111 QAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDF--KKD 173

  Fly   140 LDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISIL 204
            .|.::...|.       |:|:.||..   ..::.::|.:.::|.||.||:..||:|:.|:.:||:
Mouse   174 TDDQESQHES-------EQDFSKGPC---PTVRQKLWDILEKPGSSTAARIFGVISIIFVAVSIV 228

  Fly   205 SFCLKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSP 269
                            |:.:.:|..|  |.      |..: ...:|.||.:|||.|.::||:...
Mouse   229 ----------------NMALMSAELS--WL------NLQL-LEILEYVCISWFTGEFVLRFLCVK 268

  Fly   270 NKWEFIKSSVNIIDYIATLSFYIDLVLQRFA-SH----LENAD-ILEFFSIIRIMRLFKLTRHSS 328
            ::..|::...||||.:|.|.|||.|:::..: ||    |||.. :::...::|.:|:.||.|||:
Mouse   269 DRCHFLRKVPNIIDLLAILPFYITLLVESLSGSHTTQELENVGRLVQVLRLLRALRMLKLGRHST 333

  Fly   329 GLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTV 393
            ||:.|..|.....:|:.||:.||.:||.||:::.|:||  |..|...|.|:|...|||..:||||
Mouse   334 GLRSLGMTITQCYEEVGLLLLFLSVGISIFSTIEYFAE--QSIPDTTFTSVPCAWWWATTSMTTV 396

  Fly   394 GYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYY 435
            ||||:.|.|..|..|..:|.|:|:|.:|||:.:|...|:..|
Mouse   397 GYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACY 438

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ShawNP_001137782.1 BTB 27..125 CDD:197585 40/114 (35%)
BTB_2 27..117 CDD:280393 37/106 (35%)
Ion_trans 244..439 CDD:278921 78/198 (39%)
Ion_trans_2 355..429 CDD:285168 34/73 (47%)
Kcnv1NP_080476.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..20
BTB_POZ 44..163 CDD:365784 40/116 (34%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 171..192 7/27 (26%)
Ion_trans 212..438 CDD:366146 89/252 (35%)
Selectivity filter. /evidence=ECO:0000250 395..400 4/4 (100%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2126
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D818306at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X19
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.820

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