Protein Alignment Shaw and Kcng4

DIOPT Version :9

• Sequence 1: NP_001137782.1
• Gene: Shaw / 33599
• FlyBaseID: FBgn0003386
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_080010.2
• Gene: Kcng4 / 66733
• MGIID: 1913983
• Length: 506
• Species: Mus musculus
• Alignment Length: 471
• Identity: 142/471 - (30%)
• Similarity: 227/471 - (48%)
• Gaps: 60/471 - (12%)

  Fly     5 PKKMQH-YAHAAMNLINMDSE-----NRVVLNVGGIRHETYKATLKKIPATRLSRL--------- 54
            ||.::. |...|..:.|.|:.     ..:::||||.|:....:||...|.:|||||
Mouse    32 PKSVKGLYYSRARKVGNQDASPEANLKEILVNVGGQRYLLPWSTLDAFPLSRLSRLRLCRSHEEI 96

  Fly    55 TEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCW 119
            |:...:||....|:||||:|..|..::::...|||....::|...|.|||.:||::...:|.||
Mouse    97 TQLCDDYDEDSQEFFFDRNPSAFGVIVSFLAAGKLVLLREMCALSFREELSYWGIEETNLERCC- 160

  Fly   120 MTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYS 184
                       ...:|.:|:...|...||...|:...:..:.:...|.|.....::..:.::|.|
Mouse   161 -----------LRKLLKKLEEAAELRREEAAQRQQQRQACHSEVQASRWARSMNQLREMVEDPQS 214

  Fly   185 SNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYI 249
            ....|....:||.|:..:.:|.|:.|.||.|           |....|   :.|:...:|  |.:
Mouse   215 GLPGKVFACLSVLFVATTAVSLCVSTMPDFR-----------AEEGKG---ECTRKCYYI--FVV 263

  Fly   250 ECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQ----------RFASHLE 304
            |.:|.|||:.|..:||:.:|||.:|.:..:|:||.:|...:|:.|.:.          ..:|:||
Mouse   264 ESICVAWFSLEFCLRFVQAPNKCQFFRGPLNVIDILAISPYYVSLAVSDESPEAGERPSSSSYLE 328

  Fly   305 NAD-ILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERI 368
            ... :|.....:||:.:.:|.|||.||:.|..|.|..|:|..||:.||.:.:.:|:.|||.||.
Mouse   329 KVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCAREFGLLMLFLAVAVTLFSPLVYVAEN- 392

  Fly   369 QPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAM 433
            :.....:|.|||...|||:::|||||||||.|::..|..|.....|:|:|.:|.|...|...|:.
Mouse   393 ESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSH 457

  Fly   434 YY-----SHTQARAKL 444
            .|     ...|.:|:|
Mouse   458 SYLELKREQEQVQARL 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585	36/106 (34%)
		BTB_2	27..117	CDD:280393	34/98 (35%)
		Ion_trans	244..439	CDD:278921	74/210 (35%)
		Ion_trans_2	355..429	CDD:285168	31/73 (42%)
Kcng4	NP_080010.2	BTB_POZ	58..167	CDD:365784	37/120 (31%)
		Ion_trans	219..463	CDD:366146	87/260 (33%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	416..421		4/4 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810