DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shaw and kcna7

DIOPT Version :9

Sequence 1:	NP_001137782.1	Gene:	Shaw / 33599	FlyBaseID:	FBgn0003386	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	XP_701294.4	Gene:	kcna7 / 572481	ZFINID:	ZDB-GENE-120215-257	Length:	233	Species:	Danio rerio

Alignment Length:	200	Identity:	60/200 - (30%)
Similarity:	92/200 - (46%)	Gaps:	52/200 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRT-GKL 89
            |:.:||.|:|:||...||.:.|.:.|......|..:||:.||.|.||:...|..:|.:|:: |:|
Zfish    68 RLAINVSGMRYETQIRTLAQFPDSLLGDPRRRLRYFDPLRNEIFLDRNRFCFDAILYFYQSGGRL 132

  Fly    90 HYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKF 154
            ..|.:|...:|.:||.|:.|.                                     |::..:|
Zfish   133 RRPANVPLDVFMDELRFYELG-------------------------------------EDIMARF 160

  Fly   155 GFEEDYYKGTISWWQEMKP--------RIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTH 211
            ..:|.:.|      :|.:|        :||.||:.|.||..|:.|.::||..|.:|||.|||:|.
Zfish   161 KEDEGFPK------EEPRPLPESEFQRKIWMLFEHPESSGGARIIAIISVMVIVVSILIFCLETL 219

  Fly   212 PDMRV 216
            ||.||
Zfish   220 PDFRV 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585	30/98 (31%)
		BTB_2	27..117	CDD:280393	30/90 (33%)
		Ion_trans	244..439	CDD:278921
		Ion_trans_2	355..429	CDD:285168
kcna7	XP_701294.4	BTB_2	71..160	CDD:280393	31/125 (25%)
kcna7	XP_701294.4	BTB	71..158	CDD:197585	31/123 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810