DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shaw and tnfaip1

DIOPT Version :9

Sequence 1:	NP_001137782.1	Gene:	Shaw / 33599	FlyBaseID:	FBgn0003386	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_001016809.1	Gene:	tnfaip1 / 549563	XenbaseID:	XB-GENE-943703	Length:	319	Species:	Xenopus tropicalis

Alignment Length:	179	Identity:	39/179 - (21%)
Similarity:	62/179 - (34%)	Gaps:	55/179 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 LNVGG----------IRHETYKATLKKIPATRLSRLTEALANYDPILNE--YFFDRHPGVFAQVL 81
            |||||          .||:|   .||.:.:.|:..||:         .|  ...||....|..:|
Frog    35 LNVGGCLYYTTVQVLTRHDT---MLKAMFSGRMEVLTD---------KEGWILIDRCGKHFGSIL 87

  Fly    82 NYYRTGKLHYPT---DVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTE 143
            ||.|...:..|.   :|...:.|.:   :.|....|:.|    ....:|..:|...:..:.:.|.
Frog    88 NYLRDDTITLPKSRHEVKELMAEAK---YYLIQGLVDKC----QAALQDKNDTYEAVCNIPIITS 145

  Fly   144 KPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDE-----PYSSNA 187
            ...||:|..                ...||.:..|::.     .|:||:
Frog   146 PKEEEKLIE----------------SSAKPVVKLLYNRSNNKYSYTSNS 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585	27/110 (25%)
		BTB_2	27..117	CDD:280393	26/102 (25%)
		Ion_trans	244..439	CDD:278921
		Ion_trans_2	355..429	CDD:285168
tnfaip1	NP_001016809.1	BTB_POZ_TNFAIP1_BACURD2	29..132	CDD:349709	28/115 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910