DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shaw and tmem184c

DIOPT Version :9

Sequence 1:	NP_001137782.1	Gene:	Shaw / 33599	FlyBaseID:	FBgn0003386	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_001016532.1	Gene:	tmem184c / 549286	XenbaseID:	XB-GENE-1016397	Length:	443	Species:	Xenopus tropicalis

Alignment Length:	248	Identity:	49/248 - (19%)
Similarity:	77/248 - (31%)	Gaps:	102/248 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   233 WFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKW------------EFIKSSVNII--- 282
            |.|.|.:...|         ..|||...|.|......:.|            |..|..:.|:
Frog    33 WKLQKMEVGVH---------TKAWFIAGIFVLMTIPISLWGILQHLVHYTQPELQKPIIRILWMV 88

  Fly   283 ------DYIA----TLSFYIDLVLQRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTF 337
                  .:||    .::.|:|...:.:.:::    |..|.    |..|..||.....|.::::.
Frog    89 PIYSVDSWIALKYPDIAIYVDTCRECYEAYV----IYNFM----IFLLNYLTNRCPNLALVLEA- 144

  Fly   338 RASAKEL------------TLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTM 390
            :...:.|            .:|:|...||:     |.|...|            |:....||:..
Frog   145 KDQQRHLPPLCCCPPWAMGDVLLFRCKLGV-----LQYTVVR------------PVTTVIALICQ 192

  Fly   391 TT--VGYGDMAPK---TYIGMFVGALCALAGVLTIALPVPVIVSN----FAMY 434
            .|  .|.||.:.|   ||:                     ||::|    ||||
Frog   193 LTGVYGEGDFSVKNAWTYL---------------------VIINNVSQVFAMY 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585
		BTB_2	27..117	CDD:280393
		Ion_trans	244..439	CDD:278921	45/237 (19%)
		Ion_trans_2	355..429	CDD:285168	15/78 (19%)
tmem184c	NP_001016532.1	Solute_trans_a	46..312	CDD:367581	45/226 (20%)
tmem184c	NP_001016532.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	369..422
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000