Protein Alignment Shaw and Kcnf1

DIOPT Version :9

• Sequence 1: NP_001137782.1
• Gene: Shaw / 33599
• FlyBaseID: FBgn0003386
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_963289.2
• Gene: Kcnf1 / 382571
• MGIID: 2687399
• Length: 505
• Species: Mus musculus
• Alignment Length: 470
• Identity: 155/470 - (32%)
• Similarity: 228/470 - (48%)
• Gaps: 79/470 - (16%)

  Fly    27 VVLNVGGIRHETYKATLKKIPATRLSRLTEALA-----------NYDPILNEYFFDRHPGVFAQV 80
            :|:||||:|...|...|.:.|.|||:.|...||           :|||...|::|||.|..|..|
Mouse    37 IVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPDAFKCV 101

  Fly    81 LNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLA-----VLDRLDL 140
            :..|..|::|....:|...|:.|::||.:|...::.||....::.|:..|.:|     :||.|.:
Mouse   102 IEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIARRVQLILDDLGV 166

  Fly   141 DTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILS 205
            |..:                     ..|:..:..:|...::|.||..|:.:.|:|...|.:|.:.
Mouse   167 DAAE---------------------GRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVV 210

  Fly   206 FCLKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPN 270
            .|:.|.|:::|.......|:                 |.....:|..|..|||.|.|:|..||||
Mouse   211 MCMGTIPELQVVDSEGNRVE-----------------HPTLENVETACIGWFTLEYLLRLFSSPN 258

  Fly   271 KWEFIKSSVNIIDYIATLSFYIDLVLQRFAS---HLENA-DILEFFSIIRIMRLFKLTRHSSGLK 331
            |..|..|.:||:|.:|.|.||:.|.|....:   .|.|. ..::...|:||.|:|||.||||||:
Mouse   259 KLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSSGLQ 323

  Fly   332 ILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYG 396
            .|....:.|.|||.||:.:|.:||.:|::|.|..|  |.:|...|.|||...|||::||||||||
Mouse   324 TLTYALKRSFKELGLLLMYLAVGIFVFSALGYTME--QSHPETLFKSIPQSFWWAIITMTTVGYG 386

  Fly   397 DMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPR 461
            |:.|||.:|....|:..|.||:.||||:..|::||..||:           ::|||......:..
Mouse   387 DIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYN-----------KQRVLETAAKHELE 440

  Fly   462 L--------PGAPGG 468
            |        .|.|||
Mouse   441 LMELNSSSAEGKPGG 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585	36/108 (33%)
		BTB_2	27..117	CDD:280393	34/100 (34%)
		Ion_trans	244..439	CDD:278921	88/198 (44%)
		Ion_trans_2	355..429	CDD:285168	36/73 (49%)
Kcnf1	NP_963289.2	BTB_POZ_Kv5_KCNF1	35..150	CDD:349690	37/112 (33%)
		Ion_trans	193..429	CDD:366146	99/265 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D331021at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820